Archive for April, 2008

GM Files: Monsanto’s War on Food and Freedom

Friday, April 18th, 2008

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www.organics4U.orgMonsanto’s Harvest of Fear
Monsanto already dominates America’s food chain with its genetically modified seeds. Now it has targeted milk production. Just as frightening as the corporation’s tactics–ruthless legal battles against small farmers–is its decades-long history of toxic contamination.
by Donald L. Barlett and James B. Steele May 2008

http://www.vanityfair.com/images/politics/2008/05/poar03_monsanto0805.jpg

Gary Rinehart clearly remembers the summer day in 2002 when the stranger walked in and issued his threat. Rinehart was behind the counter of the Square Deal, his “old-time country store,” as he calls it, on the fading town square of Eagleville, Missouri, a tiny farm community 100 miles north of Kansas City.

The Square Deal is a fixture in Eagleville, a place where farmers and townspeople can go for lightbulbs, greeting cards, hunting gear, ice cream, aspirin, and dozens of other small items without having to drive to a big-box store in Bethany, the county seat, 15 miles down Interstate 35.

Everyone knows Rinehart, who was born and raised in the area and runs one of Eagleville’s few surviving businesses. The stranger came up to the counter and asked for him by name.

“Well, that’s me,” said Rinehart.

As Rinehart would recall, the man began verbally attacking him, saying he had proof that Rinehart had planted Monsanto’s genetically modified (G.M.) soybeans in violation of the company’s patent. Better come clean and settle with Monsanto, Rinehart says the man told him—or face the consequences.

Rinehart was incredulous, listening to the words as puzzled customers and employees looked on. Like many others in rural America, Rinehart knew of Monsanto’s fierce reputation for enforcing its patents and suing anyone who allegedly violated them. But Rinehart wasn’t a farmer. He wasn’t a seed dealer. He hadn’t planted any seeds or sold any seeds. He owned a small—a really small—country store in a town of 350 people. He was angry that somebody could just barge into the store and embarrass him in front of everyone. “It made me and my business look bad,” he says. Rinehart says he told the intruder, “You got the wrong guy.”

When the stranger persisted, Rinehart showed him the door. On the way out the man kept making threats. Rinehart says he can’t remember the exact words, but they were to the effect of: “Monsanto is big. You can’t win. We will get you. You will pay.”

Scenes like this are playing out in many parts of rural America these days as Monsanto goes after farmers, farmers’ co-ops, seed dealers—anyone it suspects may have infringed its patents of genetically modified seeds. As interviews and reams of court documents reveal, Monsanto relies on a shadowy army of private investigators and agents in the American heartland to strike fear into farm country. They fan out into fields and farm towns, where they secretly videotape and photograph farmers, store owners, and co-ops; infiltrate community meetings; and gather information from informants about farming activities. Farmers say that some Monsanto agents pretend to be surveyors. Others confront farmers on their land and try to pressure them to sign papers giving Monsanto access to their private records. Farmers call them the “seed police” and use words such as “Gestapo” and “Mafia” to describe their tactics.

When asked about these practices, Monsanto declined to comment specifically, other than to say that the company is simply protecting its patents. “Monsanto spends more than $2 million a day in research to identify, test, develop and bring to market innovative new seeds and technologies that benefit farmers,” Monsanto spokesman Darren Wallis wrote in an e-mailed letter to Vanity Fair. “One tool in protecting this investment is patenting our discoveries and, if necessary, legally defending those patents against those who might choose to infringe upon them.” Wallis said that, while the vast majority of farmers and seed dealers follow the licensing agreements, “a tiny fraction” do not, and that Monsanto is obligated to those who do abide by its rules to enforce its patent rights on those who “reap the benefits of the technology without paying for its use.” He said only a small number of cases ever go to trial.

Some compare Monsanto’s hard-line approach to Microsoft’s zealous efforts to protect its software from pirates. At least with Microsoft the buyer of a program can use it over and over again. But farmers who buy Monsanto’s seeds can’t even do that.
The Control of Nature

For centuries—millennia—farmers have saved seeds from season to season: they planted in the spring, harvested in the fall, then reclaimed and cleaned the seeds over the winter for re-planting the next spring. Monsanto has turned this ancient practice on its head.

Monsanto developed G.M. seeds that would resist its own herbicide, Roundup, offering farmers a convenient way to spray fields with weed killer without affecting crops. Monsanto then patented the seeds. For nearly all of its history the United States Patent and Trademark Office had refused to grant patents on seeds, viewing them as life-forms with too many variables to be patented. “It’s not like describing a widget,” says Joseph Mendelson III, the legal director of the Center for Food Safety, which has tracked Monsanto’s activities in rural America for years.

Indeed not. But in 1980 the U.S. Supreme Court, in a five-to-four decision, turned seeds into widgets, laying the groundwork for a handful of corporations to begin taking control of the world’s food supply. In its decision, the court extended patent law to cover “a live human-made microorganism.” In this case, the organism wasn’t even a seed. Rather, it was a Pseudomonas bacterium developed by a General Electric scientist to clean up oil spills. But the precedent was set, and Monsanto took advantage of it. Since the 1980s, Monsanto has become the world leader in genetic modification of seeds and has won 674 biotechnology patents, more than any other company, according to U.S. Department of Agriculture data.
Monsanto’s Harvest of Fear
Monsanto already dominates America’s food chain with its genetically modified seeds. Now it has targeted milk production. Just as frightening as the corporation’s tactics–ruthless legal battles against small farmers–is its decades-long history of toxic contamination.
by Donald L. Barlett and James B. Steele May 2008

http://www.vanityfair.com/images/politics/2008/05/poar03_monsanto0805.jpg

Farmers who buy Monsanto’s patented Roundup Ready seeds are required to sign an agreement promising not to save the seed produced after each harvest for re-planting, or to sell the seed to other farmers. This means that farmers must buy new seed every year. Those increased sales, coupled with ballooning sales of its Roundup weed killer, have been a bonanza for Monsanto.

This radical departure from age-old practice has created turmoil in farm country. Some farmers don’t fully understand that they aren’t supposed to save Monsanto’s seeds for next year’s planting. Others do, but ignore the stipulation rather than throw away a perfectly usable product. Still others say that they don’t use Monsanto’s genetically modified seeds, but seeds have been blown into their fields by wind or deposited by birds. It’s certainly easy for G.M. seeds to get mixed in with traditional varieties when seeds are cleaned by commercial dealers for re-planting. The seeds look identical; only a laboratory analysis can show the difference. Even if a farmer doesn’t buy G.M. seeds and doesn’t want them on his land, it’s a safe bet he’ll get a visit from Monsanto’s seed police if crops grown from G.M. seeds are discovered in his fields.

Most Americans know Monsanto because of what it sells to put on our lawns— the ubiquitous weed killer Roundup. What they may not know is that the company now profoundly influences—and one day may virtually control—what we put on our tables. For most of its history Monsanto was a chemical giant, producing some of the most toxic substances ever created, residues from which have left us with some of the most polluted sites on earth. Yet in a little more than a decade, the company has sought to shed its polluted past and morph into something much different and more far-reaching—an “agricultural company” dedicated to making the world “a better place for future generations.” Still, more than one Web log claims to see similarities between Monsanto and the fictional company “U-North” in the movie Michael Clayton, an agribusiness giant accused in a multibillion-dollar lawsuit of selling an herbicide that causes cancer. http://www.vanityfair.com/images/politics/2008/05/poar01_monsanto0805.jpg

Monsanto’s genetically modified seeds have transformed the company and are radically altering global agriculture. So far, the company has produced G.M. seeds for soybeans, corn, canola, and cotton. Many more products have been developed or are in the pipeline, including seeds for sugar beets and alfalfa. The company is also seeking to extend its reach into milk production by marketing an artificial growth hormone for cows that increases their output, and it is taking aggressive steps to put those who don’t want to use growth hormone at a commercial disadvantage.

Even as the company is pushing its G.M. agenda, Monsanto is buying up conventional-seed companies. In 2005, Monsanto paid $1.4 billion for Seminis, which controlled 40 percent of the U.S. market for lettuce, tomatoes, and other vegetable and fruit seeds. Two weeks later it announced the acquisition of the country’s third-largest cottonseed company, Emergent Genetics, for $300 million. It’s estimated that Monsanto seeds now account for 90 percent of the U.S. production of soybeans, which are used in food products beyond counting. Monsanto’s acquisitions have fueled explosive growth, transforming the St. Louis–based corporation into the largest seed company in the world.

In Iraq, the groundwork has been laid to protect the patents of Monsanto and other G.M.-seed companies. One of L. Paul Bremer’s last acts as head of the Coalition Provisional Authority was an order stipulating that “farmers shall be prohibited from re-using seeds of protected varieties.” Monsanto has said that it has no interest in doing business in Iraq, but should the company change its mind, the American-style law is in place.

To be sure, more and more agricultural corporations and individual farmers are using Monsanto’s G.M. seeds. As recently as 1980, no genetically modified crops were grown in the U.S. In 2007, the total was 142 million acres planted. Worldwide, the figure was 282 million acres. Many farmers believe that G.M. seeds increase crop yields and save money. Another reason for their attraction is convenience. By using Roundup Ready soybean seeds, a farmer can spend less time tending to his fields. With Monsanto seeds, a farmer plants his crop, then treats it later with Roundup to kill weeds. That takes the place of labor-intensive weed control and plowing.

Monsanto portrays its move into G.M. seeds as a giant leap for mankind. But out in the American countryside, Monsanto’s no-holds-barred tactics have made it feared and loathed. Like it or not, farmers say, they have fewer and fewer choices in buying seeds.

And controlling the seeds is not some abstraction. Whoever provides the world’s seeds controls the world’s food supply.
Under Surveillance

After Monsanto’s investigator confronted Gary Rinehart, Monsanto filed a federal lawsuit alleging that Rinehart “knowingly, intentionally, and willfully” planted seeds “in violation of Monsanto’s patent rights.” The company’s complaint made it sound as if Monsanto had Rinehart dead to rights:

During the 2002 growing season, Investigator Jeffery Moore, through surveillance of Mr. Rinehart’s farm facility and farming operations, observed Defendant planting brown bag soybean seed. Mr. Moore observed the Defendant take the brown bag soybeans to a field, which was subsequently loaded into a grain drill and planted. Mr. Moore located two empty bags in the ditch in the public road right-of-way beside one of the fields planted by Rinehart, which contained some soybeans. Mr. Moore collected a small amount of soybeans left in the bags which Defendant had tossed into the public right-of way. These samples tested positive for Monsanto’s Roundup Ready technology.

Faced with a federal lawsuit, Rinehart had to hire a lawyer. Monsanto eventually realized that “Investigator Jeffery Moore” had targeted the wrong man, and dropped the suit. Rinehart later learned that the company had been secretly investigating farmers in his area. Rinehart never heard from Monsanto again: no letter of apology, no public concession that the company had made a terrible mistake, no offer to pay his attorney’s fees. “I don’t know how they get away with it,” he says. “If I tried to do something like that it would be bad news. I felt like I was in another country.”

Gary Rinehart is actually one of Monsanto’s luckier targets. Ever since commercial introduction of its G.M. seeds, in 1996, Monsanto has launched thousands of investigations and filed lawsuits against hundreds of farmers and seed dealers. In a 2007 report, the Center for Food Safety, in Washington, D.C., documented 112 such lawsuits, in 27 states.

Even more significant, in the Center’s opinion, are the numbers of farmers who settle because they don’t have the money or the time to fight Monsanto. “The number of cases filed is only the tip of the iceberg,” says Bill Freese, the Center’s science-policy analyst. Freese says he has been told of many cases in which Monsanto investigators showed up at a farmer’s house or confronted him in his fields, claiming he had violated the technology agreement and demanding to see his records. According to Freese, investigators will say, “Monsanto knows that you are saving Roundup Ready seeds, and if you don’t sign these information-release forms, Monsanto is going to come after you and take your farm or take you for all you’re worth.” Investigators will sometimes show a farmer a photo of himself coming out of a store, to let him know he is being followed.

Lawyers who have represented farmers sued by Monsanto say that intimidating actions like these are commonplace. Most give in and pay Monsanto some amount in damages; those who resist face the full force of Monsanto’s legal wrath.
Scorched-Earth Tactics

Pilot Grove, Missouri, population 750, sits in rolling farmland 150 miles west of St. Louis. The town has a grocery store, a bank, a bar, a nursing home, a funeral parlor, and a few other small businesses. There are no stoplights, but the town doesn’t need any. The little traffic it has comes from trucks on their way to and from the grain elevator on the edge of town. The elevator is owned by a local co-op, the Pilot Grove Cooperative Elevator, which buys soybeans and corn from farmers in the fall, then ships out the grain over the winter. The co-op has seven full-time employees and four computers.

In the fall of 2006, Monsanto trained its legal guns on Pilot Grove; ever since, its farmers have been drawn into a costly, disruptive legal battle against an opponent with limitless resources. Neither Pilot Grove nor Monsanto will discuss the case, but it is possible to piece together much of the story from documents filed as part of the litigation.

Monsanto began investigating soybean farmers in and around Pilot Grove several years ago. There is no indication as to what sparked the probe, but Monsanto periodically investigates farmers in soybean-growing regions such as this one in central Missouri. The company has a staff devoted to enforcing patents and litigating against farmers. To gather leads, the company maintains an 800 number and encourages farmers to inform on other farmers they think may be engaging in “seed piracy.”

Once Pilot Grove had been targeted, Monsanto sent private investigators into the area. Over a period of months, Monsanto’s investigators surreptitiously followed the co-op’s employees and customers and videotaped them in fields and going about other activities. At least 17 such surveillance videos were made, according to court records. The investigative work was outsourced to a St. Louis agency, McDowell & Associates. It was a McDowell investigator who erroneously fingered Gary Rinehart. In Pilot Grove, at least 11 McDowell investigators have worked the case, and Monsanto makes no bones about the extent of this effort: “Surveillance was conducted throughout the year by various investigators in the field,” according to court records. McDowell, like Monsanto, will not comment on the case.

Not long after investigators showed up in Pilot Grove, Monsanto subpoenaed the co-op’s records concerning seed and herbicide purchases and seed-cleaning operations. The co-op provided more than 800 pages of documents pertaining to dozens of farmers. Monsanto sued two farmers and negotiated settlements with more than 25 others it accused of seed piracy. But Monsanto’s legal assault had only begun. Although the co-op had provided voluminous records, Monsanto then sued it in federal court for patent infringement. Monsanto contended that by cleaning seeds—a service which it had provided for decades—the co-op was inducing farmers to violate Monsanto’s patents. In effect, Monsanto wanted the co-op to police its own customers.

In the majority of cases where Monsanto sues, or threatens to sue, farmers settle before going to trial. The cost and stress of litigating against a global corporation are just too great. But Pilot Grove wouldn’t cave—and ever since, Monsanto has been turning up the heat. The more the co-op has resisted, the more legal firepower Monsanto has aimed at it. Pilot Grove’s lawyer, Steven H. Schwartz, described Monsanto in a court filing as pursuing a “scorched earth tactic,” intent on “trying to drive the co-op into the ground.”

Even after Pilot Grove turned over thousands more pages of sales records going back five years, and covering virtually every one of its farmer customers, Monsanto wanted more—the right to inspect the co-op’s hard drives. When the co-op offered to provide an electronic version of any record, Monsanto demanded hands-on access to Pilot Grove’s in-house computers.

Monsanto next petitioned to make potential damages punitive—tripling the amount that Pilot Grove might have to pay if found guilty. After a judge denied that request, Monsanto expanded the scope of the pre-trial investigation by seeking to quadruple the number of depositions. “Monsanto is doing its best to make this case so expensive to defend that the Co-op will have no choice but to relent,” Pilot Grove’s lawyer said in a court filing.

With Pilot Grove still holding out for a trial, Monsanto now subpoenaed the records of more than 100 of the co-op’s customers. In a “You are Commanded … ” notice, the farmers were ordered to gather up five years of invoices, receipts, and all other papers relating to their soybean and herbicide purchases, and to have the documents delivered to a law office in St. Louis. Monsanto gave them two weeks to comply.

Whether Pilot Grove can continue to wage its legal battle remains to be seen. Whatever the outcome, the case shows why Monsanto is so detested in farm country, even by those who buy its products. “I don’t know of a company that chooses to sue its own customer base,” says Joseph Mendelson, of the Center for Food Safety. “It’s a very bizarre business strategy.” But it’s one that Monsanto manages to get away with, because increasingly it’s the dominant vendor in town.
Chemicals? What Chemicals?

The Monsanto Company has never been one of America’s friendliest corporate citizens. Given Monsanto’s current dominance in the field of bioengineering, it’s worth looking at the company’s own DNA. The future of the company may lie in seeds, but the seeds of the company lie in chemicals. Communities around the world are still reaping the environmental consequences of Monsanto’s origins.

Monsanto was founded in 1901 by John Francis Queeny, a tough, cigar-smoking Irishman with a sixth-grade education. A buyer for a wholesale drug company, Queeny had an idea. But like a lot of employees with ideas, he found that his boss wouldn’t listen to him. So he went into business for himself on the side. Queeny was convinced there was money to be made manufacturing a substance called saccharin, an artificial sweetener then imported from Germany. He took $1,500 of his savings, borrowed another $3,500, and set up shop in a dingy warehouse near the St. Louis waterfront. With borrowed equipment and secondhand machines, he began producing saccharin for the U.S. market. He called the company the Monsanto Chemical Works, Monsanto being his wife’s maiden name.

The German cartel that controlled the market for saccharin wasn’t pleased, and cut the price from $4.50 to $1 a pound to try to force Queeny out of business. The young company faced other challenges. Questions arose about the safety of saccharin, and the U.S. Department of Agriculture even tried to ban it. Fortunately for Queeny, he wasn’t up against opponents as aggressive and litigious as the Monsanto of today. His persistence and the loyalty of one steady customer kept the company afloat. That steady customer was a new company in Georgia named Coca-Cola.

Monsanto added more and more products—vanillin, caffeine, and drugs used as sedatives and laxatives. In 1917, Monsanto began making aspirin, and soon became the largest maker worldwide. During World War I, cut off from imported European chemicals, Monsanto was forced to manufacture its own, and its position as a leading force in the chemical industry was assured.

After Queeny was diagnosed with cancer, in the late 1920s, his only son, Edgar, became president. Where the father had been a classic entrepreneur, Edgar Monsanto Queeny was an empire builder with a grand vision. It was Edgar—shrewd, daring, and intuitive (“He can see around the next corner,” his secretary once said)—who built Monsanto into a global powerhouse. Under Edgar Queeny and his successors, Monsanto extended its reach into a phenomenal number of products: plastics, resins, rubber goods, fuel additives, artificial caffeine, industrial fluids, vinyl siding, dishwasher detergent, anti-freeze, fertilizers, herbicides, pesticides. Its safety glass protects the U.S. Constitution and the Mona Lisa. Its synthetic fibers are the basis of Astroturf.

During the 1970s, the company shifted more and more resources into biotechnology. In 1981 it created a molecular-biology group for research in plant genetics. The next year, Monsanto scientists hit gold: they became the first to genetically modify a plant cell. “It will now be possible to introduce virtually any gene into plant cells with the ultimate goal of improving crop productivity,” said Ernest Jaworski, director of Monsanto’s Biological Sciences Program.

Over the next few years, scientists working mainly in the company’s vast new Life Sciences Research Center, 25 miles west of St. Louis, developed one genetically modified product after another—cotton, soybeans, corn, canola. From the start, G.M. seeds were controversial with the public as well as with some farmers and European consumers. Monsanto has sought to portray G.M. seeds as a panacea, a way to alleviate poverty and feed the hungry. Robert Shapiro, Monsanto’s president during the 1990s, once called G.M. seeds “the single most successful introduction of technology in the history of agriculture, including the plow.”

By the late 1990s, Monsanto, having rebranded itself into a “life sciences” company, had spun off its chemical and fibers operations into a new company called Solutia. After an additional reorganization, Monsanto re-incorporated in 2002 and officially declared itself an “agricultural company.”

In its company literature, Monsanto now refers to itself disingenuously as a “relatively new company” whose primary goal is helping “farmers around the world in their mission to feed, clothe, and fuel” a growing planet. In its list of corporate milestones, all but a handful are from the recent era. As for the company’s early history, the decades when it grew into an industrial powerhouse now held potentially responsible for more than 50 Environmental Protection Agency Superfund sites—none of that is mentioned. It’s as though the original Monsanto, the company that long had the word “chemical” as part of its name, never existed. One of the benefits of doing this, as the company does not point out, was to channel the bulk of the growing backlog of chemical lawsuits and liabilities onto Solutia, keeping the Monsanto brand pure.

But Monsanto’s past, especially its environmental legacy, is very much with us. For many years Monsanto produced two of the most toxic substances ever known— polychlorinated biphenyls, better known as PCBs, and dioxin. Monsanto no longer produces either, but the places where it did are still struggling with the aftermath, and probably always will be.
“Systemic Intoxication”

Twelve miles downriver from Charleston, West Virginia, is the town of Nitro, where Monsanto operated a chemical plant from 1929 to 1995. In 1948 the plant began to make a powerful herbicide known as 2,4,5-T, called “weed bug” by the workers. A by-product of the process was the creation of a chemical that would later be known as dioxin.

The name dioxin refers to a group of highly toxic chemicals that have been linked to heart disease, liver disease, human reproductive disorders, and developmental problems. Even in small amounts, dioxin persists in the environment and accumulates in the body. In 1997 the International Agency for Research on Cancer, a branch of the World Health Organization, classified the most powerful form of dioxin as a substance that causes cancer in humans. In 2001 the U.S. government listed the chemical as a “known human carcinogen.”On March 8, 1949, a massive explosion rocked Monsanto’s Nitro plant when a pressure valve blew on a container cooking up a batch of herbicide. The noise from the release was a scream so loud that it drowned out the emergency steam whistle for five minutes. A plume of vapor and white smoke drifted across the plant and out over town.Residue from the explosion coated the interior of the building and those inside with what workers described as “a fine black powder.” Many felt their skin prickle and were told to scrub down.

Within days, workers experienced skin eruptions. Many were soon diagnosed with chloracne, a condition similar to common acne but more severe, longer lasting, and potentially disfiguring. Others felt intense pains in their legs, chest, and trunk. A confidential medical report at the time said the explosion “caused a systemic intoxication in the workers involving most major organ systems.” Doctors who examined four of the most seriously injured men detected a strong odor coming from them when they were all together in a closed room. “We believe these men are excreting a foreign chemical through their skins,” the confidential report to Monsanto noted. Court records indicate that 226 plant workers became ill.

According to court documents that have surfaced in a West Virginia court case, Monsanto downplayed the impact, stating that the contaminant affecting workers was “fairly slow acting” and caused “only an irritation of the skin.”

In the meantime, the Nitro plant continued to produce herbicides, rubber products, and other chemicals. In the 1960s, the factory manufactured Agent Orange, the powerful herbicide which the U.S. military used to defoliate jungles during the Vietnam War, and which later was the focus of lawsuits by veterans contending that they had been harmed by exposure. As with Monsanto’s older herbicides, the manufacturing of Agent Orange created dioxin as a by-product.

As for the Nitro plant’s waste, some was burned in incinerators, some dumped in landfills or storm drains, some allowed to run into streams. As Stuart Calwell, a lawyer who has represented both workers and residents in Nitro, put it, “Dioxin went wherever the product went, down the sewer, shipped in bags, and when the waste was burned, out in the air.”

In 1981 several former Nitro employees filed lawsuits in federal court, charging that Monsanto had knowingly exposed them to chemicals that caused long-term health problems, including cancer and heart disease. They alleged that Monsanto knew that many chemicals used at Nitro were potentially harmful, but had kept that information from them. On the eve of a trial, in 1988, Monsanto agreed to settle most of the cases by making a single lump payment of $1.5 million. Monsanto also agreed to drop its claim to collect $305,000 in court costs from six retired Monsanto workers who had unsuccessfully charged in another lawsuit that Monsanto had recklessly exposed them to dioxin. Monsanto had attached liens to the retirees’ homes to guarantee collection of the debt.

Monsanto stopped producing dioxin in Nitro in 1969, but the toxic chemical can still be found well beyond the Nitro plant site. Repeated studies have found elevated levels of dioxin in nearby rivers, streams, and fish. Residents have sued to seek damages from Monsanto and Solutia. Earlier this year, a West Virginia judge merged those lawsuits into a class-action suit. A Monsanto spokesman said, “We believe the allegations are without merit and we’ll defend ourselves vigorously.” The suit will no doubt take years to play out. Time is one thing that Monsanto always has, and that the plaintiffs usually don’t.
Poisoned Lawns

Five hundred miles to the south, the people of Anniston, Alabama, know all about what the people of Nitro are going through. They’ve been there. In fact, you could say, they’re still there.

From 1929 to 1971, Monsanto’s Anniston works produced PCBs as industrial coolants and insulating fluids for transformers and other electrical equipment. One of the wonder chemicals of the 20th century, PCBs were exceptionally versatile and fire-resistant, and became central to many American industries as lubricants, hydraulic fluids, and sealants. But PCBs are toxic. A member of a family of chemicals that mimic hormones, PCBs have been linked to damage in the liver and in the neurological, immune, endocrine, and reproductive systems. The Environmental Protection Agency (E.P.A.) and the Agency for Toxic Substances and Disease Registry, part of the Department of Health and Human Services, now classify PCBs as “probable carcinogens.”

Today, 37 years after PCB production ceased in Anniston, and after tons of contaminated soil have been removed to try to reclaim the site, the area around the old Monsanto plant remains one of the most polluted spots in the U.S.

People in Anniston find themselves in this fix today largely because of the way Monsanto disposed of PCB waste for decades. Excess PCBs were dumped in a nearby open-pit landfill or allowed to flow off the property with storm water. Some waste was poured directly into Snow Creek, which runs alongside the plant and empties into a larger stream, Choccolocco Creek. PCBs also turned up in private lawns after the company invited Anniston residents to use soil from the plant for their lawns, according to The Anniston Star.

So for decades the people of Anniston breathed air, planted gardens, drank from wells, fished in rivers, and swam in creeks contaminated with PCBs—without knowing anything about the danger. It wasn’t until the 1990s—20 years after Monsanto stopped making PCBs in Anniston—that widespread public awareness of the problem there took hold.

Studies by health authorities consistently found elevated levels of PCBs in houses, yards, streams, fields, fish, and other wildlife—and in people. In 2003, Monsanto and Solutia entered into a consent decree with the E.P.A. to clean up Anniston. Scores of houses and small businesses were to be razed, tons of contaminated soil dug up and carted off, and streambeds scooped of toxic residue. The cleanup is under way, and it will take years, but some doubt it will ever be completed—the job is massive. To settle residents’ claims, Monsanto has also paid $550 million to 21,000 Anniston residents exposed to PCBs, but many of them continue to live with PCBs in their bodies. Once PCB is absorbed into human tissue, there it forever remains.

Monsanto shut down PCB production in Anniston in 1971, and the company ended all its American PCB operations in 1977. Also in 1977, Monsanto closed a PCB plant in Wales. In recent years, residents near the village of Groesfaen, in southern Wales, have noticed vile odors emanating from an old quarry outside the village. As it turns out, Monsanto had dumped thousands of tons of waste from its nearby PCB plant into the quarry. British authorities are struggling to decide what to do with what they have now identified as among the most contaminated places in Britain.
“No Cause for Public Alarm”

What had Monsanto known—or what should it have known—about the potential dangers of the chemicals it was manufacturing? There’s considerable documentation lurking in court records from many lawsuits indicating that Monsanto knew quite a lot. Let’s look just at the example of PCBs.

The evidence that Monsanto refused to face questions about their toxicity is quite clear. In 1956 the company tried to sell the navy a hydraulic fluid for its submarines called Pydraul 150, which contained PCBs. Monsanto supplied the navy with test results for the product. But the navy decided to run its own tests. Afterward, navy officials informed Monsanto that they wouldn’t be buying the product. “Applications of Pydraul 150 caused death in all of the rabbits tested” and indicated “definite liver damage,” navy officials told Monsanto, according to an internal Monsanto memo divulged in the course of a court proceeding. “No matter how we discussed the situation,” complained Monsanto’s medical director, R. Emmet Kelly, “it was impossible to change their thinking that Pydraul 150 is just too toxic for use in submarines.”

Ten years later, a biologist conducting studies for Monsanto in streams near the Anniston plant got quick results when he submerged his test fish. As he reported to Monsanto, according to The Washington Post, “All 25 fish lost equilibrium and turned on their sides in 10 seconds and all were dead in 3½ minutes.”

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When the Food and Drug Administration (F.D.A.) turned up high levels of PCBs in fish near the Anniston plant in 1970, the company swung into action to limit the P.R. damage. An internal memo entitled “confidential—f.y.i. and destroy” from Monsanto official Paul B. Hodges reviewed steps under way to limit disclosure of the information. One element of the strategy was to get public officials to fight Monsanto’s battle: “Joe Crockett, Secretary of the Alabama Water Improvement Commission, will try to handle the problem quietly without release of the information to the public at this time,” according to the memo.

Despite Monsanto’s efforts, the information did get out, but the company was able to blunt its impact. Monsanto’s Anniston plant manager “convinced” a reporter for The Anniston Star that there was really nothing to worry about, and an internal memo from Monsanto’s headquarters in St. Louis summarized the story that subsequently appeared in the newspaper: “Quoting both plant management and the Alabama Water Improvement Commission, the feature emphasized the PCB problem was relatively new, was being solved by Monsanto and, at this point, was no cause for public alarm.”

In truth, there was enormous cause for public alarm. But that harm was done by the “Original Monsanto Company,” not “Today’s Monsanto Company” (the words and the distinction are Monsanto’s). The Monsanto of today says that it can be trusted—that its biotech crops are “as wholesome, nutritious and safe as conventional crops,” and that milk from cows injected with its artificial growth hormone is the same as, and as safe as, milk from any other cow.
The Milk Wars

Jeff Kleinpeter takes very good care of his dairy cows. In the winter he turns on heaters to warm their barns. In the summer, fans blow gentle breezes to cool them, and on especially hot days, a fine mist floats down to take the edge off Louisiana’s heat. The dairy has gone “to the ultimate end of the earth for cow comfort,” says Kleinpeter, a fourth-generation dairy farmer in Baton Rouge. He says visitors marvel at what he does: “I’ve had many of them say, ‘When I die, I want to come back as a Kleinpeter cow.’ ”

Monsanto would like to change the way Jeff Kleinpeter and his family do business. Specifically, Monsanto doesn’t like the label on Kleinpeter Dairy’s milk cartons: “From Cows Not Treated with rBGH.” To consumers, that means the milk comes from cows that were not given artificial bovine growth hormone, a supplement developed by Monsanto that can be injected into dairy cows to increase their milk output.

No one knows what effect, if any, the hormone has on milk or the people who drink it. Studies have not detected any difference in the quality of milk produced by cows that receive rBGH, or rBST, a term by which it is also known. But Jeff Kleinpeter—like millions of consumers—wants no part of rBGH. Whatever its effect on humans, if any, Kleinpeter feels certain it’s harmful to cows because it speeds up their metabolism and increases the chances that they’ll contract a painful illness that can shorten their lives. “It’s like putting a Volkswagen car in with the Indianapolis 500 racers,” he says. “You gotta keep the pedal to the metal the whole way through, and pretty soon that poor little Volkswagen engine’s going to burn up.”

Kleinpeter Dairy has never used Monsanto’s artificial hormone, and the dairy requires other dairy farmers from whom it buys milk to attest that they don’t use it, either. At the suggestion of a marketing consultant, the dairy began advertising its milk as coming from rBGH-free cows in 2005, and the label began appearing on Kleinpeter milk cartons and in company literature, including a new Web site of Kleinpeter products that proclaims, “We treat our cows with love … not rBGH.”

The dairy’s sales soared. For Kleinpeter, it was simply a matter of giving consumers more information about their product.

But giving consumers that information has stirred the ire of Monsanto. The company contends that advertising by Kleinpeter and other dairies touting their “no rBGH” milk reflects adversely on Monsanto’s product. In a letter to the Federal Trade Commission in February 2007, Monsanto said that, notwithstanding the overwhelming evidence that there is no difference in the milk from cows treated with its product, “milk processors persist in claiming on their labels and in advertisements that the use of rBST is somehow harmful, either to cows or to the people who consume milk from rBST-supplemented cows.”

Monsanto called on the commission to investigate what it called the “deceptive advertising and labeling practices” of milk processors such as Kleinpeter, accusing them of misleading consumers “by falsely claiming that there are health and safety risks associated with milk from rBST-supplemented cows.” As noted, Kleinpeter does not make any such claims—he simply states that his milk comes from cows not injected with rBGH.

Monsanto’s attempt to get the F.T.C. to force dairies to change their advertising was just one more step in the corporation’s efforts to extend its reach into agriculture. After years of scientific debate and public controversy, the F.D.A. in 1993 approved commercial use of rBST, basing its decision in part on studies submitted by Monsanto. That decision allowed the company to market the artificial hormone. The effect of the hormone is to increase milk production, not exactly something the nation needed then—or needs now. The U.S. was actually awash in milk, with the government buying up the surplus to prevent a collapse in prices.

Monsanto began selling the supplement in 1994 under the name Posilac. Monsanto acknowledges that the possible side effects of rBST for cows include lameness, disorders of the uterus, increased body temperature, digestive problems, and birthing difficulties. Veterinary drug reports note that “cows injected with Posilac are at an increased risk for mastitis,” an udder infection in which bacteria and pus may be pumped out with the milk. What’s the effect on humans? The F.D.A. has consistently said that the milk produced by cows that receive rBGH is the same as milk from cows that aren’t injected: “The public can be confident that milk and meat from BST-treated cows is safe to consume.” Nevertheless, some scientists are concerned by the lack of long-term studies to test the additive’s impact, especially on children. A Wisconsin geneticist, William von Meyer, observed that when rBGH was approved the longest study on which the F.D.A.’s approval was based covered only a 90-day laboratory test with small animals. “But people drink milk for a lifetime,” he noted. Canada and the European Union have never approved the commercial sale of the artificial hormone. Today, nearly 15 years after the F.D.A. approved rBGH, there have still been no long-term studies “to determine the safety of milk from cows that receive artificial growth hormone,” says Michael Hansen, senior staff scientist for Consumers Union. Not only have there been no studies, he adds, but the data that does exist all comes from Monsanto. “There is no scientific consensus about the safety,” he says.

However F.D.A. approval came about, Monsanto has long been wired into Washington. Michael R. Taylor was a staff attorney and executive assistant to the F.D.A. commissioner before joining a law firm in Washington in 1981, where he worked to secure F.D.A. approval of Monsanto’s artificial growth hormone before returning to the F.D.A. as deputy commissioner in 1991. Dr. Michael A. Friedman, formerly the F.D.A.’s deputy commissioner for operations, joined Monsanto in 1999 as a senior vice president. Linda J. Fisher was an assistant administrator at the E.P.A. when she left the agency in 1993. She became a vice president of Monsanto, from 1995 to 2000, only to return to the E.P.A. as deputy administrator the next year. William D. Ruckelshaus, former E.P.A. administrator, and Mickey Kantor, former U.S. trade representative, each served on Monsanto’s board after leaving government. Supreme Court justice Clarence Thomas was an attorney in Monsanto’s corporate-law department in the 1970s. He wrote the Supreme Court opinion in a crucial G.M.-seed patent-rights case in 2001 that benefited Monsanto and all G.M.-seed companies. Donald Rumsfeld never served on the board or held any office at Monsanto, but Monsanto must occupy a soft spot in the heart of the former defense secretary. Rumsfeld was chairman and C.E.O. of the pharmaceutical maker G. D. Searle & Co. when Monsanto acquired Searle in 1985, after Searle had experienced difficulty in finding a buyer. Rumsfeld’s stock and options in Searle were valued at $12 million at the time of the sale.

From the beginning some consumers have consistently been hesitant to drink milk from cows treated with artificial hormones. This is one reason Monsanto has waged so many battles with dairies and regulators over the wording of labels on milk cartons. It has sued at least two dairies and one co-op over labeling.

Critics of the artificial hormone have pushed for mandatory labeling on all milk products, but the F.D.A. has resisted and even taken action against some dairies that labeled their milk “BST-free.” Since BST is a natural hormone found in all cows, including those not injected with Monsanto’s artificial version, the F.D.A. argued that no dairy could claim that its milk is BST-free. The F.D.A. later issued guidelines allowing dairies to use labels saying their milk comes from “non-supplemented cows,” as long as the carton has a disclaimer saying that the artificial supplement does not in any way change the milk. So the milk cartons from Kleinpeter Dairy, for example, carry a label on the front stating that the milk is from cows not treated with rBGH, and the rear panel says, “Government studies have shown no significant difference between milk derived from rBGH-treated and non-rBGH-treated cows.” That’s not good enough for Monsanto.
The Next Battleground

As more and more dairies have chosen to advertise their milk as “No rBGH,” Monsanto has gone on the offensive. Its attempt to force the F.T.C. to look into what Monsanto called “deceptive practices” by dairies trying to distance themselves from the company’s artificial hormone was the most recent national salvo. But after reviewing Monsanto’s claims, the F.T.C.’s Division of Advertising Practices decided in August 2007 that a “formal investigation and enforcement action is not warranted at this time.” The agency found some instances where dairies had made “unfounded health and safety claims,” but these were mostly on Web sites, not on milk cartons. And the F.T.C. determined that the dairies Monsanto had singled out all carried disclaimers that the F.D.A. had found no significant differences in milk from cows treated with the artificial hormone.

Blocked at the federal level, Monsanto is pushing for action by the states. In the fall of 2007, Pennsylvania’s agriculture secretary, Dennis Wolff, issued an edict prohibiting dairies from stamping milk containers with labels stating their products were made without the use of the artificial hormone. Wolff said such a label implies that competitors’ milk is not safe, and noted that non-supplemented milk comes at an unjustified higher price, arguments that Monsanto has frequently made. The ban was to take effect February 1, 2008.

Wolff’s action created a firestorm in Pennsylvania (and beyond) from angry consumers. So intense was the outpouring of e-mails, letters, and calls that Pennsylvania governor Edward Rendell stepped in and reversed his agriculture secretary, saying, “The public has a right to complete information about how the milk they buy is produced.”

On this issue, the tide may be shifting against Monsanto. Organic dairy products, which don’t involve rBGH, are soaring in popularity. Supermarket chains such as Kroger, Publix, and Safeway are embracing them. Some other companies have turned away from rBGH products, including Starbucks, which has banned all milk products from cows treated with rBGH. Although Monsanto once claimed that an estimated 30 percent of the nation’s dairy cows were injected with rBST, it’s widely believed that today the number is much lower.

But don’t count Monsanto out. Efforts similar to the one in Pennsylvania have been launched in other states, including New Jersey, Ohio, Indiana, Kansas, Utah, and Missouri. A Monsanto-backed group called afact—American Farmers for the Advancement and Conservation of Technology—has been spearheading efforts in many of these states. afact describes itself as a “producer organization” that decries “questionable labeling tactics and activism” by marketers who have convinced some consumers to “shy away from foods using new technology.” afact reportedly uses the same St. Louis public-relations firm, Osborn & Barr, employed by Monsanto. An Osborn & Barr spokesman told The Kansas City Star that the company was doing work for afact on a pro bono basis.

Even if Monsanto’s efforts to secure across-the-board labeling changes should fall short, there’s nothing to stop state agriculture departments from restricting labeling on a dairy-by-dairy basis. Beyond that, Monsanto also has allies whose foot soldiers will almost certainly keep up the pressure on dairies that don’t use Monsanto’s artificial hormone. Jeff Kleinpeter knows about them, too.

He got a call one day from the man who prints the labels for his milk cartons, asking if he had seen the attack on Kleinpeter Dairy that had been posted on the Internet. Kleinpeter went online to a site called StopLabelingLies, which claims to “help consumers by publicizing examples of false and misleading food and other product labels.” There, sure enough, Kleinpeter and other dairies that didn’t use Monsanto’s product were being accused of making misleading claims to sell their milk.

There was no address or phone number on the Web site, only a list of groups that apparently contribute to the site and whose issues range from disparaging organic farming to downplaying the impact of global warming. “They were criticizing people like me for doing what we had a right to do, had gone through a government agency to do,” says Kleinpeter. “We never could get to the bottom of that Web site to get that corrected.”

As it turns out, the Web site counts among its contributors Steven Milloy, the “junk science” commentator for FoxNews.com and operator of junkscience.com, which claims to debunk “faulty scientific data and analysis.” It may come as no surprise that earlier in his career, Milloy, who calls himself the “junkman,” was a registered lobbyist for Monsanto.

Donald L. Barlett and James B. Steele are Vanity Fair contributing editors.

GM Files:COMPANY RESEARCH ON GENETICALLY MODIFIED FOODS IS RIGGED

Friday, April 18th, 2008

The Natural Solutions Foundation, the leading Global Health Freedom organization, is proud to present this information to you. We protect your right to know about – and to use – natural ways to maintain and regain your health, no matter where in the world you live. Among your freedoms is the right to clean, unadulterated food free of genetic manipulation, pesticides, heavy metals or other contaminants and access to herbs, supplements, frequency devices and other means as therapies that may benefit or to protect your well-being without drugs and other dangerous interventions, if you choose.

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COMPANY RESEARCH ON GENETICALLY MODIFIED FOODS IS RIGGED

In 2004, four advocates of genetically modified (GM) foods published a study in the British Food Journal that was sure to boost their cause [1]. According to the peer-reviewed paper, when shoppers in a Canadian farm store were confronted with an informed and unbiased choice between GM corn and non-GM corn, most purchased the GM variety. This finding flew in the face of worldwide consumer resistance to GM foods, which had shut markets in Europe, Japan, and elsewhere. It also challenged studies that showed that the more information on genetically modified organisms (GMOs) consumers have, the less they trust them.[2] The study, which was funded by the biotech-industry front group, Council for Biotechnology Information and the industry’s trade association, the Crop Protection Institute of Canada (now Croplife Canada), was given the Journal’s prestigious Award for Excellence for the Most Outstanding Paper of 2004 and has been cited often by biotech advocates.

Stuart Laidlaw, a reporter from Canada’s Toronto Star, visited the farm store several times during the study and described the scenario in his book Secret Ingredients. Far from offering unbiased choices, key elements appeared rigged to favor GM corn purchases. The consumer education fact sheets were entirely pro-GMO, and Doug Powell, the lead researcher, enthusiastically demonstrated to Laidlaw how he could convince shoppers to buy the GM varieties. He confronted a farmer who had already purchased non-GM corn. After pitching his case for GMOs, Powell proudly had the farmer tell Laidlaw that he had changed his opinion and would buy GM corn in his next shopping trip.

Powell’s interference with shoppers’ “unbiased” choices was nothing compared to the effect of the signs placed over the corn bins. The sign above the non-GM corn read, “Would you eat wormy sweet corn?” It further listed the chemicals that were sprayed during the season. By contrast, the sign above the GM corn stated, “Here’s What Went into Producing Quality Sweet Corn.” It is no wonder that 60% of shoppers avoided the “wormy corn.” In fact, it may be a testament to people’s distrust of GMOs that 40% still went for the “wormy” option.

Powell and his colleagues did not mention the controversial signage in their study. They claimed that the corn bins in the farm store were “fully labelled”—either “genetically engineered Bt sweet corn” or “Regular sweet-corn.”

When Laidlaw’s book came out, however, Powell’s “wormy” sign was featured in a photograph,[3] exposing what was later described by Cambridge University’s Dr. Richard Jennings as “flagrant fraud.” Jennings, who is a leading researcher on scientific ethics, says, “It was a sin of omission by failing to divulge information which quite clearly should have been disclosed.”[4]

Jennings is among several scientists and outraged citizens that say the paper should have been withdrawn, but the Journal refused. Instead, it published a criticism of the methods by Canadian geneticist Joe Cummins, and allowed Powell to respond with a lengthy reply.[5]

In his defence, Powell claimed that his signs merely used the language of consumers and was “not intended to manipulate consumer purchasing patterns.” He also claimed that the “wormy” corn sign was only there for the first week of the trial and was then replaced by other educational messages. But eye witnesses and photographs demonstrate the presence of the sign long after Powell’s suggested date of replacement.[6]

This incident illustrates how so-called scientific papers can be manipulated to force conclusions favorable to authors or funders and how peer-reviewed journals may be complicit. While the subject of this particular study provided ammunition in the battle to deny choice to consumers in North America, there is similar “cooked” research in the more critical area of GMO safety assessments.

SECRET, INADEQUATE, AND FLAWED
THE UNPUBLISHED INDUSTRY STUDIES SUBMITTED TO REGULATORS ARE TYPICALLY KEPT SECRET BASED ON THE CLAIM THAT IT IS “CONFIDENTIAL BUSINESS INFORMATION.” THE ROYAL SOCIETY OF CANADA IS ONE OF MANY ORGANIZATIONS THAT CONDEMN THIS PRACTICE. THEY WROTE:
IN THE JUDGMENT OF THE EXPERT PANEL, THE MORE REGULATORY AGENCIES LIMIT FREE ACCESS TO THE DATA UPON WHICH THEIR DECISIONS ARE BASED, THE MORE COMPROMISED BECOMES THE CLAIM THAT THE REGULATORY PROCESS IS ‘SCIENCE BASED.’ THIS IS DUE TO A SIMPLE BUT WELL-UNDERSTOOD REQUIREMENT OF THE SCIENTIFIC METHOD ITSELF—THAT IT BE AN OPEN, COMPLETELY TRANSPARENT ENTERPRISE IN WHICH ANY AND ALL ASPECTS OF SCIENTIFIC RESEARCH ARE OPEN TO FULL REVIEW BY SCIENTIFIC PEERS. PEER REVIEW AND INDEPENDENT CORROBORATION OF RESEARCH FINDINGS ARE AXIOMS OF THE SCIENTIFIC METHOD, AND PART OF THE VERY MEANING OF THE OBJECTIVITY AND NEUTRALITY OF SCIENCE.”[7]

Whenever private submissions are made public through lawsuits or Freedom of Information Act Requests, it becomes clear why companies benefit from secrecy. The quality of their research is often miserable, incompetent, and unacceptable for peer-review. In 2000, for example, after the potentially allergenic StarLink corn was discovered in the food supply, Aventis CropScience presented wholly inadequate safety data to the EPA’s scientific advisory panel. One frustrated panel member, Dean Metcalfe, MD,—the government’s top allergist—said during a hearing, “Most of us review for a lot of journals. And if this were presented for publication in the journals that I review for, it would be sent back to the authors with all of these questions. It would be rejected.”[8]

Submissions to the US Food and Drug Administraion (FDA) may be worse than in other countries, since the agency doesn’t actually require any data. Their policy—overseen by Monsanto’s former attorney who later became the company’s vice president—says that biotech companies can determine if their own foods are safe. Anything submitted is voluntary and, according to former Environmental Protection Agency scientist Doug Gurian-Sherman, “often lack[s] sufficient detail, such as necessary statistical analyses needed for an adequate safety evaluation.” Using Freedom of Information Requests, Gurian-Sherman analyzed more than a fourth of the data summaries (14 of 53) of GM crops reviewed by the FDA. He says, “Our evaluation found that the biotechnology companies provide inadequate data to ensure their products are safe.”[9]

UNSCIENTIFIC ASSUMPTIONS ARE THE BASIS OF APPROVALS

“Most or all of the conclusions of food safety for individual GM crops are based on inferences and assumptions, rather than on actual testing,” says Professor E. Ann Clark, who analyzed submissions to Canadian regulators. For example, rather than actually testing to see if the amino acid sequence produced by their inserted gene is correct, “the standard practice,” according to research analyst William Freese, “is to sequence just 5 to 25 amino acids, even if the protein has more than 600 in total. If the short sample matches what is expected, they assume that the rest are also fine. If they are wrong, however, a rearranged protein could be quite dangerous.”

Monsanto’s submission to Australian regulators on their high lysine GM corn provides several examples of optimistic assumptions used in place of science. The GM protein produced in the corn is also found in soil. The company claimed that since people consume small residues of soil on fruits and vegetables, the protein has a history of safe consumption. An independent calculation by the Centre for Integrated Research on Biosafety (INBI), however, reveals the weakness of this argument. Based on the amount of GM corn protein an average US citizen would consume (if all their corn were Monsanto’s variety), “for equivalent exposure” of the protein from soil “people would have to eat between 80-800 million (males) or 60-700 million (females) kilograms of soil each day, or nearly as much as 10,000kg/second 24 hours a day seven days a week.” INBI estimated that the normal exposure to the protein from soil residues was actually “about 30 billion-4 trillion times less than exposure through [high lysine] corn.”[10]

In addition, certain nutritional components of this GM variety (i.e. protein content, total dietary fiber, acid detergent fiber, and neutral detergent fiber) lie far outside the normal range for corn. Instead of comparing their corn to normal controls, which would reveal this disparity, Monsanto compared it to obscure corn varieties that were also substantially outside the normal range on precisely these values.

Epidemiologist Judy Carman points out that GM “experiments used some very unusual animal models for human health, such as chickens, cows and trout. Some of the measurements taken from these animals are also unusual measures of human health, such as abdominal fat pad weight, total de-boned breast meat yield, and milk production.” In her examination of the full range of submittals to authorities in Australia and New Zealand, she says that there was no proper evaluation of “biochemistry, immunology, tissue pathology, and gut, liver and kidney function.”[11] Writing on behalf of the Public Health Association of Australia, Carman says, “The effects of feeding people high concentrations of the new protein over tens of years cannot be determined by feeding 20 mice a single oral gavage of a given high concentration of the protein and taking very basic data for 13-14 days . . .The acute toxicity testing proposed as adequate would simply not pick up cancer, teratology [birth defects] or the long-tem effects of nutrient deficiencies or increases in anti-nutrients.”[12]

THE SCIENCE OF RIGGING STUDIES

When independent researchers published a study in July 1999 showing that GM soy contains 12%-14% less cancer-fighting phytoestrogens, Monsanto responded with its own study, concluding that soy’s phytoestrogen levels vary too much to even carry out a statistical analysis. Researchers failed to disclose, however, that they had instructed the laboratory to use an obsolete method of detection—one that had been prone to highly variable results.[13]
WHEN AVENTIS PREPARED SAMPLES TO SEE IF THE POTENTIAL ALLERGEN IN STARLINK CORN REMAINED INTACT AFTER COOKING, INSTEAD OF USING THE STANDARD 30-MINUTE TREATMENT, THEY HEATED CORN FOR TWO HOURS.
TO SHOW THAT PASTEURIZATION DESTROYED BOVINE GROWTH HORMONE IN MILK FROM COWS TREATED WITH RBGH, THEY PASTEURIZED THE MILK 120 TIMES LONGER THAN NORMAL. UNABLE TO DESTROY MORE THAN 19%, THEY THEN SPIKED THE MILK WITH A HUGE AMOUNT OF THE HORMONE AND REPEATED THE LONG PASTEURIZATION, DESTROYING 90%. (THE FDA REPORTED THAT PASTEURIZATION DESTROYS 90% OF THE HORMONE.)
TO DEMONSTRATE THAT INJECTIONS OF RBGH DID NOT INTERFERE WITH COW’S FERTILITY, MONSANTO APPARENTLY ADDED COWS TO THE STUDY THAT WERE PREGNANT PRIOR TO INJECTION.

AND IN ORDER TO PROVE THAT THE PROTEIN FROM THEIR GM CROPS BREAKS DOWN QUICKLY DURING SIMULATED DIGESTION, BIOTECH COMPANIES USED THOUSANDS OF TIMES THE AMOUNT OF DIGESTIVE ENZYMES AND A MUCH STRONGER ACID COMPARED TO THAT RECOMMENDED BY THE WORLD HEALTH ORGANIZATION.

METHODS USED TO HIDE PROBLEMS ARE VARIED AND PLENTIFUL. FOR EXAMPLE, RESEARCHERS:

USE HIGHLY VARIABLE ANIMAL STARTING WEIGHTS TO HINDER DETECTION OF FOOD-RELATED CHANGES

KEEP FEEDING STUDIES SHORT TO MISS LONG-TERM IMPACTS

TEST EFFECTS OF ROUNDUP READY SOYBEANS THAT HAVE NOT BEEN SPRAYED WITH ROUNDUP

AVOID FEEDING ANIMALS THE ACTUAL GM CROP, BUT GIVE THEM INSTEAD A SINGLE DOSE OF THE GM PROTEIN THAT WAS PRODUCED INSIDE GM BACTERIA

USE TOO FEW SUBJECTS TO DERIVE STATISTICALLY SIGNIFICANT RESULTS

USE POOR STATISTICAL METHODS OR SIMPLY LEAVE OUT ESSENTIAL METHODS, DATA, OR STATISTICS

USE RIGGED OR IRRELEVANT CONTROL GROUPS, AND
EMPLOY INSENSITIVE OR OBSOLETE EVALUATION TECHNIQUES

Monsanto’s 1996 Journal of Nutrition study[14],[15] provides plenty of examples of scientific transgressions. Roundup Ready soybeans are engineered to withstand the normally fatal effects of Monsanto’s herbicide called Roundup. Monsanto scientists published a feeding study that purported to test their soybeans’ effect on rats, catfish, chickens, and cows. The study has been used often by the industry as validation for safety claims. According to Dr. Arpad Pusztai, however, “It was obvious that the study had been designed to avoid finding any problems. Everybody in our consortium knew this.” Pusztai was commissioned at the time by the UK government to develop rigorous testing protocols on GM foods—protocols that were never implemented. Pusztai, who had published several studies in that same nutrition journal, said the Monsanto paper was “not really up to the normal journal standards.” Pusztai says that if he had been asked to referee the paper for publication, “it would never have passed.” He’s confident that even his graduate assistants would have taken the study apart in short order. Some of the flaws include:

*
Researchers tested GM soy on mature animals, not young ones. Young animals use protein to build their muscles, tissues, and organs. Problems with GM food could therefore show up in organ and body weight. But adult animals use the protein for tissue renewal and energy. “With a nutritional study on mature animals,” says Pusztai, “you would never see any difference in organ weights even if the food turned out to be anti-nutritional. The animals would have to be emaciated or poisoned to show anything.”
*
Even if there were an organ development problem, the study wouldn’t have picked it up since the researchers didn’t weigh the organs.
*
In one of the trials, researchers substituted only one tenth of the natural protein with GM soy protein. In two others, they diluted their GM soy six- and twelve-fold. [16] Scientists Ian Pryme of Norway and Rolf Lembcke of Denmark wrote, the “level of the GM soy was too low, and would probably ensure that any possible undesirable GM effects did not occur.”
*
Pryme and Lembcke, who published a paper in Nutrition and Health that analyzed all peer-reviewed feeding studies on GM foods as of 2003, also pointed out that the percentage of protein in the feed used in the Roundup Ready study was “artificially too high.” This “would almost certainly mask, or at least effectively reduce, any possible effect of the [GM soy].” They said it was “highly likely that all GM effects would have been diluted out.” [17]
*
Proper compositional studies filter out effects of weather or geography by comparing plants grown at the same time in the same location. Monsanto, however, pooled data from several locations, which makes it difficult for differences to be statistically significant. Nonetheless, the data revealed significant differences in the ash, fat, and carbohydrate content. Roundup Ready soy meal also contained 27% more trypsin inhibitor, a potential allergen, which might explain the sudden jump in soy allergies in the UK beginning right after Roundup Ready soy was introduced. Also, cows fed GM soy produced milk with a higher fat content, demonstrating another disparity between the two types of soy.
*
One field trial, however, did grow GM and non-GM plants next to each other, but this data was not included in the paper. Years after the study appeared, medical writer Barbara Keeler discovered the data that had been omitted. It showed that Monsanto’s GM soy had significantly lower levels of protein, a fatty acid, and phenylalanine, an essential amino acid. Also, toasted GM soy meal contained nearly twice the amount of a lectin—one that may interfere with the body’s ability to assimilate other nutrients. And the amount of trypsin inhibitor in cooked GM soy was as much as seven times higher than a cooked non-GM control.
*
The study also omitted many details normally required for a published paper. According to Pryme and Lembcke, “No data were given for most of the parameters.”
*
And when researchers tested the effects of Roundup Ready protein on animals, they didn’t extract the protein from the soybeans. Instead, they derived it from GM bacteria, claiming the two forms of protein were equivalent. There are numerous ways, however, in which the protein in the soy may be different. In fact, nine years after this study was published, another study showed that the gene inserted into the soybeans produced unintended aberrant RNA strands, meaning that the protein may be quite different than what was intended.[18]

In Pryme and Lembcke’s analysis, it came as no surprise that this Monsanto study, along with the other four peer-reviewed animal feeding studies that were “performed more or less in collaboration with private companies,” reported no negative effects of the GM diet. “On the other hand,” they wrote, “adverse effects were reported (but not explained) in [the five] independent studies.” They added, “It is remarkable that these effects have all been observed after feeding for only 10–14 days.”[19]

TOXIC GM FOODS COULD HAVE BEEN APPROVED

Two GM foods whose commercialization was stopped because of negative test results give a chilling example of what may be getting through. Rats fed GM potatoes had potentially precancerous cell growth in the stomach and intestines, less developed brains, livers, and testicles, partial atrophy of the liver, and damaged immune systems.[20] GM peas provoked an inflammatory response in mice, suggesting that the peas might trigger a deadly anaphylactic shock in allergic humans.[21] Both of these dangerous crops, however, could easily have been approved. The problems were only discovered because the researchers used advanced tests that were never applied to GM crops already on the market. Both would have passed the normal tests that companies typically use to get their products approved.

Ironically, when Monsanto was asked to comment on the pea study, their spokesperson said it demonstrated that the regulatory system works. He failed to disclose that none of the company’s GM crops had been put through such rigorous tests.

RAMPANT UNRELENTING INDUSTRY BIAS

Industry-funded research that favors the funders is not new. Bias has been identified across several industries. In pharmaceuticals, for example, positive results are four times more likely if the drug’s manufacturer funds the study.[22] When companies pay for the economic analyses of their own cancer drugs, the results are eight times more likely to be favorable.[23] Compared to drug research, the potential for industry manipulation in GM crop studies is considerably higher. Unlike pharmaceutical testing, GM research has no standardized procedures dictated by regulators. GM studies are not usually published in peer-reviewed journals and are typically kept secret by companies and governments. There is little money available for rigorous independent research, so company evidence usually goes unchallenged and unverified. Most importantly, whereas drugs can show serious side-effects and still be approved, GM food cannot. There is no tolerance for adverse reactions; feeding trials must show no problems.

Thus, when industry studies show problems (in spite of their efforts to avoid them), serious adverse reactions and even deaths among GM-fed animals are ignored or dismissed as “not biologically significant” or due to “natural variations.”

Numerous reports including peer-reviewed articles and part 3 of the book Genetic Roulette are replete with examples of rigged research. But making these public does not seem to curtail its practice. Consider the wormy corn of the British Food Journal. Not only has the editor refused to retract the paper, he has not even agreed to reconsider its Award for Excellence. A blatant propaganda exercise still stands validated as exemplary science.

In the critical arena of food safety research, where the health of society is caught in the balance, it is entirely unacceptable that the biotech industry is without accountability, standards, or peer-review. At our expense, they’ve got bad science down to a science.
THIS ARTICLE IS BASED ON PART 3 OF THE BOOK, GENETIC ROULETTE: THE DOCUMENTED HEALTH RISKS OF GENETICALLY ENGINEERED FOODS, BY JEFFREY M. SMITH. www.GeneticRoulette.com

Jeffrey M. Smith is the author of the new publication Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods, which presents 65 risks in easy-to-read two-page spreads. His first book, Seeds of Deception, is the top rated and #1 selling book on GM foods in the world. He is the Executive Director of the Institute for Responsible Technology, which is spearheading the Campaign for Healthier Eating in America. Go to www.seedsofdeception.com to learn more about how to avoid GM foods.

[1] Powell D.A.; Blaine K.; Morris S.; Wilson J., Agronomic and consumer considerations for Bt and conventional sweet-corn, British Food Journal, Volume: 105, Issue: 10, Page: 700-713 (Nov 2003)

[2] GM Nation? The findings of the public debate, http://www.gmnation.org.uk/ut_09/ut_9_6.htm#summary

[3] To see the Toronto Star photo in Laidlaw’s book, go to http://www.gmwatch.org/p1temp.asp?pid=72&page=1

[4] Corn Fakes, Private Eye, No. 1194, 28 September-11 October 2007 http://www.gmwatch.org/archive2.asp?arcid=8314

[5] Editorial and letters, British Food Journal 2006 Vol : 108 Issue: 8 (August 2006)

http://www.foodsafetynetwork.ca/en/article-details.php?a=3&c=9&sc=62&id=897

[6] Tim Lambert, Would you eat wormy corn?, September 7 2007 http://scienceblogs.com/deltoid/2007/09/would_you_eat_wormy_sweet_corn.php

[7] “Elements of Precaution: Recommendations for the Regulation of Food Biotechnology in Canada; An Expert Panel Report on the Future of Food Biotechnology prepared by The Royal Society of Canada at the request of Health Canada Canadian Food Inspection Agency and Environment Canada” The Royal Society of Canada, January 2001.

[8] FIFRA Scientific Advisory Panel (SAP), Open Meeting, July 17, 2001.

[9] Doug Gurian-Sherman, “Holes in the Biotech Safety Net, FDA Policy Does Not Assure the Safety of Genetically Engineered Foods,” Center for Science in the Public Interest, http://www.cspinet.org/new/pdf/fda_report__final.pdf

[10] M. Cretenet, J. Goven, J. A. Heinemann, B. Moore, and C. Rodriguez-Beltran, “Submission on the DAR for application A549 Food Derived from High-Lysine Corn LY038: to permit the use in food of high-lysine corn, 2006, www.inbi.canterbury.ac.nz

[11] Judy Carman, “Is GM Food Safe to Eat?” in R. Hindmarsh, G. Lawrence, eds., Recoding Nature Critical Perspectives on Genetic Engineering (Sydney: UNSW Press, 2004): 82–93.

[12] FLRAG, “Comments to ANZFA about Applications A346, A362 and A363,” http://www.iher.org.au/

[13] Marc Lappé and Britt Bailey, “ASA Response,” June 25, 1999, http://cetos.org/articles/asaresponse.html

[14] S. R. Padgette, N. B.Taylor, D. L. Nida, M. R. Bailey, J. MacDonald, L. R. Holden, R. L. Fuchs, “The composition of glyphosate-tolerant soybean seeds is equivalent to that of conventional soybeans,” J. Nutr. 126 (1996):702–716.

[15] B. G. Hammond, J. L. Vicini, G. F. Hartnell, M. W. Naylor, C. D. Knight, E. H. Robinson, R. L. Fuchs, and S. R. Padgette, “The feeding value of soybeans fed to rats, chickens, catfish, and dairy cattle is not altered by genetic incorporation of glyphosate tolerance,” J. Nutr. 126 (1996): 717–727.

[16] A. Pusztai and S. Bardocz, “GMO in animal nutrition: potential benefits and risks,” Chapter 17, Biology of Nutrition in Growing Animals (Elsevier, October 2005). earlier

[17] Ian F. Pryme and Rolf Lembcke, “In Vivo Studies on Possible Health Consequences of Genetically Modified Food and Feed—with Particular Regard to Ingredients Consisting of Genetically Modified Plan Materials,” Nutrition and Health 17(2003): 1–8.

[18] Andreas Rang, et al, “Detection of RNA variants transcribed from the transgene in Roundup Ready soybean,” Eur Food

Res Technol 220 (2005): 438–443.

[19] Ian F. Pryme and Rolf Lembcke, “In Vivo Studies on Possible Health Consequences of Genetically Modified Food and Feed—with Particular Regard to Ingredients Consisting of Genetically Modified Plan Materials,” Nutrition and Health 17(2003): 1–8.

[20] Arpad Pusztai, “Can science give us the tools for recognizing possible health risks of GM food,” Nutrition and Health, 2002, Vol 16 Pp 73-84; Stanley W. B. Ewen and Arpad Pusztai, “Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine,” Lancet, 1999 Oct 16; 354 (9187): 1353-4; Arpad Pusztai, “Genetically Modified Foods: Are They a Risk to Human/Animal Health?” June 2001 Action Bioscience http://www.actionbioscience.org/biotech/pusztai.html; and A. Pusztai and S. Bardocz, “GMO in animal nutrition: potential benefits and risks,” Chapter 17, Biology of Nutrition in Growing Animals, R. Mosenthin, J. Zentek and T. Zebrowska (Eds.) Elsevier, October 2005

[21] V. E. Prescott, et al, “Transgenic Expression of Bean r-Amylase Inhibitor in Peas Results in Altered Structure and Immunogenicity,” Journal of Agricultural Food Chemistry (2005): 53.

[22] J. Lexchin, L. A. Bero, B. Djulbegovic, and O. Clark, “Pharmaceutical industry sponsorship and research outcome and quality: systematic review,” BMJ 326 (2003):1167–1176.

[23] Mark Friedberg, et al, “Evaluation of Conflict of Interest in Economic Analyses of New Drugs Used in Oncology,” JAMA 282 (1999):1453–1457.

GM Files: GMO Food May Cause Food Allergy Increases, Part 2

Friday, April 18th, 2008

The Natural Solutions Foundation, the leading Global Health Freedom organization, is proud to present this information to you. We protect your right to know about – and to use – natural ways to maintain and regain your health, no matter where in the world you live. Among your freedoms is the right to clean, unadulterated food free of genetic manipulation, pesticides, heavy metals or other contaminants and access to herbs, supplements, frequency devices and other means as therapies that may benefit or to protect your well-being without drugs and other dangerous interventions, if you choose.

For more information on our global programs, including the International Decade of Nutrition, and our US based ones, please visit us at www.HealthFreedomUSA.org and www.GlobalHealthFreedom.org and join the free email list for the Health Freedom eAlerts to keep you in the loop, informed and active defending your right to make your own decisions about your health and wellbeing!
Our activities are supported 100% by your tax deductible donations. Please give generously (http://www.healthfreedomusa.org/index.php?page_id=189) to the Natural Solutions Foundation. Thank you for your support.
Feel free to disseminate this information as widely as possible with full attribution.
Yours in health and freedom,
Dr. Rima

Rima E. Laibow, MD
Medical Director
Natural Solutions Foundation
www.HealthFreedomUSA.org
www.GlobalHealthFreedom.org
www.organics4U.org

Genetically Engineered Foods May Cause Rising Food Allergies

Part 2: Genetically Engineered Corn

By Jeffrey M. Smith

The biotech industry is fond of saying that they offer genetically modified (GM) crops that resist pests. This might conjure up the image of insects staying away from GM crop fields. But “resisting pests” is just a euphemism for contains its own built-in pesticide. When bugs take a bite of the GM plant, the toxin splits open their stomach and kills them.

The idea that we consume that same toxic pesticide in every bite is hardly appetizing. But the biotech companies and the Environmental Protection Agency—which regulates plant produced pesticides—tell us not to worry. They contend that the pesticide called Bt (Bacillus thuringiensis) is produced naturally from a soil bacterium and has a history of safe use. Organic farmers, for example, have used solutions containing the natural bacteria for years as a method of insect control. Genetic engineers simply remove the gene that produces the Bt in bacteria and then insert it into the DNA of corn and cotton plants, so that the plant does the work, not the farmer. Moreover, they say that Bt-toxin is quickly destroyed in our stomach; and even if it survived, since humans and other mammals have no receptors for the toxin, it would not interact with us in any case.

These arguments, however, are just that—unsupported assumptions. Research tells a different story.

Bt spray is dangerous to humans

When natural Bt was sprayed over areas around Vancouver and Washington State to fight gypsy moths, about 500 people reported reactions—mostly allergy or flu-like symptoms. Six people had to go to the emergency room for allergies or asthma.[1],[2] Workers who applied Bt sprays reported eye, nose, throat, and respiratory irritation,[3] and some showed an antibody immune response in linked to Bt.[4] Farmers exposed to liquid Bt formulations had reactions including infection, an ulcer on the cornea,[5] skin irritation, burning, swelling, and redness.[6] One woman who was accidentally sprayed with Bt also developed fever, altered consciousness, and seizures.[7]

In fact, authorities have long acknowledged that “People with compromised immune systems or preexisting allergies may be particularly susceptible to the effects of Bt.”[8] The Oregon Health Division advises that “individuals with . . . physician-diagnosed causes of severe immune disorders may consider leaving the area during the actual spraying.”[9] A spray manufacturer warns, “Repeated exposure via inhalation can result in sensitization and allergic response in hypersensitive individuals.”[10] So much for the contention that Bt does not interact with humans.

As for being thoroughly destroyed in the digestive system, mouse studies disproved this as well. Mice fed Bt-toxin showed significant immune responses—as potent as cholera toxin. In addition, the Bt caused their immune system to become sensitive to formerly harmless compounds This suggests that exposure might make a person allergic to a wide range of substances.[11],[12] The EPA’s own expert advisors said that the mouse and farm worker studies above “suggest that Bt proteins could act as antigenic and allergenic sources.”[13]

The toxin in GM plants is more dangerous than natural sprays

The Bt-toxin produced in GM crops is “vastly different from the bacterial [Bt-toxins] used in organic and traditional farming and forestry.”[14] First of all, GM plants produce about 3,000-5,000 times the amount of toxin as the sprays. And the spray form is broken down within a few days to two weeks by sunlight,[15] high temperatures, or substances on the leaves of plants; and it can be “washed from leaves into the soil by rainfall,”[16] or rinsed by consumers. A Bt producing GM plant, on the other hand, continuously produces the toxin in every cell where it does not dissipate by weather and cannot be washed off.

The natural toxic produced in bacteria is inactive until it gets inside the alkaline digestive tract of an insect. Once inside, a “safety catch” is removed and the Bt becomes toxic. But scientists change the sequence the Bt gene before inserting it into GM plants. The Bt toxin it produces usually comes without the safety catch. The plant-produced Bt toxin is always active and more likely to trigger an immune response than the natural variety.[17]

Bt-toxin fails safety studies but is used nonetheless

Tests cannot verify that a GM protein introduced into the food supply for the first time will not cause allergies in some people. The World Health Organization (WHO) and UN Food and Agriculture Organization (FAO) offer criteria designed to reduce the likelihood that allergenic GM crops are approved.[18] They suggest examining a protein for 1) similarity of its amino acid sequence to known allergens, 2) digestive stability and 3) heat stability. These properties aren’t predictive of allergenicity, but their presence, according to experts, should be sufficient to reject the GM crop or at least require more testing. The Bt-toxin produced in GM corn fails all three criteria.

For example, the specific Bt-toxin found in Monsanto’s Yield Guard and Syngenta’s Bt 11 corn varieties is called Cry1AB. In 1998, an FDA researcher discovered that Cry1Ab shared a sequence of 9-12 amino acids with vitellogenin, an egg yolk allergen. The study concluded that “the similarity . . . might be sufficient to warrant additional evaluation.”[19] No additional evaluation took place.[20]

Cry1Ab is also very resistant to digestion and heat.[21] It is nearly as stable as the type of Bt-toxin produced by StarLink corn. StarLink was a GM variety not approved for human consumption because experts believed that its highly stable protein might trigger allergies.[22] Although it was grown for use in animal feed, it contaminated the US food supply in 2000. Thousands of consumers complained to food manufacturers about possible reactions and over 300 items were subject to recall. After the StarLink incident, expert advisors to the EPA had called for “surveillance and clinical assessment of exposed individuals” to “confirm the allergenicity of Bt products.”[23] Again, no such monitoring has taken place.

Bt cotton triggers allergic reactions

A 2005 report by medical investigators in India describes an ominous finding. Hundreds of agricultural workers are developing moderate or severe allergic reactions when exposed to Bt cotton. This includes those picking cotton, loading it, cleaning it, or even leaning against it. Some at a ginning factory must take antihistamines daily, in order to go to work. Reactions are only triggered with the Bt varieties.[24] Furthermore, the symptoms are virtually identical to those described by the 500 people in Vancouver and Washington who were sprayed with Bt. Only “exacerbations of asthma” were in one list and not the other (see table).

Upper respiratory

Eyes

Skin

Overall

Bt Spray

Sneezing,
runny nose,
exacerbations of asthma

Watery,
red

Itching, burning, inflammation, red, swelling

Fever,
some in hospital

Bt cotton

Sneezing,
runny nose

Watery,
red

Itching, burning, eruptions,
red, swelling

Fever,
some in hospital

(We are unaware of similar reports in the US, where 83% of the cotton is Bt. But in the US, cotton is harvested by machine, not by hand.)

The experience of the Indian workers begs the question, “How long does the Bt-toxin stay active in the cotton?” It there any risk using cotton diapers, tampons, or bandages? In the latter case, if the Bt-toxin interfered with healing it could be a disaster. With diabetics, for example, unhealed wounds may be cause for amputation.

Cottonseed is also used for cottonseed oil—used in many processed foods in the US. The normal methods used to extract oil likely destroy the toxin, although cold pressed oil may still retain some of it. Other parts of the cotton plant, however, are routinely used as animal feed. The next part of this series—focused on toxicity—presents evidence of disease and deaths associated with animals consuming Bt cotton plants.

Bt corn pollen may cause allergies

Bt-toxin is produced in GM corn and can be eaten intact. It is also in pollen, which can be breathed in. In 2003, during the time when an adjacent Bt cornfield was pollinating, virtually an entire Filipino village of about 100 people were stricken by a disease. The symptoms included headaches, dizziness, extreme stomach pain, vomiting, chest pains, fever and allergies, as well as respiratory, intestinal, and skin reactions. The symptoms appeared first in those living closest to the field, and then progressed to others by proximity. Blood samples from 39 individuals showed antibodies in response to Bt-toxin; this supports, but does not prove a link to the symptoms. When the same corn was planted in four other villages the following year, however, the symptoms returned in all four areas—only during the time of pollination.

The potential dangers of breathing GM pollen had been identified in a letter to the US FDA in 1998 by the UK Joint Food Safety and Standards Group. They had even warned that genes from inhaled pollen might transfer into the DNA of bacteria in the respiratory system.[25] Although no studies were done to verify this risk, years later UK scientists confirmed that after consuming GM soybeans, the foreign inserted genes can transfer into the DNA of gut bacteria. If this also happens with Bt genes, than years after we decide to stop eating GM corn chips, our own gut bacteria may continue to produce Bt-toxin within our intestines.

Studies show immune responses to GM crops

Studies confirm that several GM crops engineered to produce built-in pesticides provoke immune responses in animals. A Monsanto rat study on Bt corn (Mon 863), that was made public due to a lawsuit, showed a significant increase in three types of blood cells related to the immune system: basophils, lymphocytes, and total white cell counts.[26]

Australian scientists took an insecticide producing gene (not Bt) from a kidney bean and put it into a pea, in hopes of killing the pea weevil. The peas had passed the tests normally used to approve GM crops and were on the way to being commercialized. But the developers decided to employ a mouse study that had never before been used on other GM food crops. When they tested the pesticide in its natural state, i.e. the version produced within kidney beans, the protein was not harmful to mice. But that “same” protein, when produced by the kidney bean gene that was inserted into pea DNA, triggered inflammatory responses in the mice, suggesting that it would cause allergies in humans. Somehow, the protein had been changed from harmless to potentially deadly, just by being created in a different plant. Scientists believe that subtle, unpredicted changes in the pattern of sugar molecules that were attached to the protein were the cause of the problem. These types of subtle changes are not routinely analyzed in GM crops on the market.

Experimental potatoes engineered with a third type of insecticide caused immune damage to rats.[27] Blood tests showed that their immune responses were more sluggish, and organs associated with immune function also appeared to be damaged. As with the peas, the insecticide in its natural state was harmless to the rats. The cause of the health problems was therefore due to some unpredicted change brought about by the genetic engineering process. And like the peas, if the potatoes had been subjected to only the type of tests that are typically used by biotech companies to get their foods on the market, the potatoes would have been approved.

Allergic reactions are a defensive, often harmful immune system response to an external irritant. The body interprets something as foreign, different and offensive, and reacts accordingly. All GM foods, by definition, have something foreign and different. According to GM food safety expert Arpad Pusztai, “A consistent feature of all the studies done, published or unpublished, . . . indicates major problems with changes in the immune status of animals fed on various GM crops/foods.” [28]

In addition to immune responses, several studies and reports from the field provide evidence that GM foods are toxic. In the next article in this series, we look at thousands of sick, sterile and dead animals, linked to consumption of GM crops.

Jeffrey M. Smith is the author of the new publication Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods, which presents 65 risks in easy-to-read two-page spreads. His first book, Seeds of Deception, is the top rated and #1 selling book on GM foods in the world. He is the Executive Director of the Institute for Responsible Technology, which is spearheading the Campaign for Healthier Eating in America. Go to www.seedsofdeception.com to learn more about how to avoid GM foods.

[1] Washington State Department of Health, “Report of health surveillance activities: Asian gypsy moth control program,” (Olympia, WA: Washington State Dept. of Health, 1993).

[2] M. Green, et al., “Public health implications of the microbial pesticide Bacillus thuringiensis: An epidemiological study, Oregon, 1985-86,” Amer. J. Public Health 80, no. 7(1990): 848–852.

[3] M.A. Noble, P.D. Riben, and G. J. Cook, “Microbiological and epidemiological surveillance program to monitor the health effects of Foray 48B BTK spray” (Vancouver, B.C.: Ministry of Forests, Province of British Columbi, Sep. 30, 1992).

[4] A. Edamura, MD, “Affidavit of the Federal Court of Canada, Trial Division. Dale Edwards and Citizens Against Aerial Spraying vs. Her Majesty the Queen, Represented by the Minister of Agriculture,” (May 6, 1993); as reported in Carrie Swadener, “Bacillus thuringiensis (B.t.),” Journal of Pesticide Reform, 14, no, 3 (Fall 1994).

[5] J. R. Samples, and H. Buettner, “Ocular infection caused by a biological insecticide,” J. Infectious Dis. 148, no. 3 (1983): 614; as reported in Carrie Swadener, “Bacillus thuringiensis (B.t.)”, Journal of Pesticide Reform 14, no. 3 (Fall 1994)

[6] M. Green, et al., “Public health implications of the microbial pesticide Bacillus thuringiensis: An epidemiological study, Oregon, 1985-86,” Amer. J. Public Health, 80, no. 7 (1990): 848–852.

[7] A. Edamura, MD, “Affidavit of the Federal Court of Canada, Trial Division. Dale Edwards and Citizens Against Aerial Spraying vs. Her Majesty the Queen, Represented by the Minister of Agriculture,” (May 6, 1993); as reported in Carrie Swadener, “Bacillus thuringiensis (B.t.),” Journal of Pesticide Reform, 14, no, 3 (Fall 1994).

[8] Carrie Swadener, “Bacillus thuringiensis (B.t.),” Journal of Pesticide Reform 14, no. 3 (Fall 1994).

[9] Health effects of B.t.: Report of surveillance in Oregon, 1985-87.

Precautions to minimize your exposure (Salem, OR: Oregon Department

of Human Resources, Health Division, April 18, 1991).

[10] Material Safety Data Sheet for Foray 48B Flowable Concentrate (Danbury, CT: Novo Nordisk, February, 1991).

[11] Vazquez et al, “Intragastric and intraperitoneal administration of Cry1Ac protoxin from Bacillus thuringiensis induces systemic and mucosal antibody responses in mice,” Life Sciences, 64, no. 21 (1999): 1897–1912; Vazquez et al, “Characterization of the mucosal and systemic immune response induced by Cry1Ac protein from Bacillus thuringiensis HD 73 in mice,” Brazilian Journal of Medical and Biological Research 33 (2000): 147–155.

[12] Vazquez et al, “Bacillus thuringiensis Cry1Ac protoxin is a potent systemic and mucosal adjuvant,” Scandanavian Journal of Immunology 49 (1999): 578–584. See also Vazquez-Padron et al., 147 (2000b).

[13] EPA Scientific Advisory Panel, “Bt Plant-Pesticides Risk and Benefits Assessments,” March 12, 2001: 76. Available at:http://www.epa.gov/scipoly/sap/2000/october/octoberfinal.pdf

[14] Terje Traavik and Jack Heinemann, “Genetic Engineering and Omitted Health Research: Still No Answers to Ageing Questions, 2006. Cited in their quote was: G. Stotzky, “Release, persistence, and biological activity in soil of insecticidal proteins from Bacillus thuringiensis,” found in Deborah K. Letourneau and Beth E. Burrows, Genetically Engineered Organisms. Assessing Environmental and Human Health Effects (cBoca Raton, FL: CRC Press LLC, 2002), 187–222.

[15] C. M. Ignoffo, and C. Garcial, “UV-photoinactivation of cells and spores of Bacillus thuringiensis and effects of peroxidase on inactivation,” Environmental Entomology 7 (1978): 270–272.

[16] BT: An Alternative to Chemical Pesticides, Environmental Protection Division, Ministry of Environment, Government of British Columbia, Canada, http://www.env.gov.bc.ca/epd/epdpa/ipmp/fact_sheets/BTfacts.htm

[17] See for example, A. Dutton, H. Klein, J. Romeis, and F. Bigler, “Uptake of Bt-toxin by herbivores feeding on transgenic maize and consequences for the predator Chrysoperia carnea,” Ecological Entomology 27 (2002): 441–7; and J. Romeis, A. Dutton, and F. Bigler, “Bacillus thuringiensis toxin (Cry1Ab) has no direct effect on larvae of the green lacewing Chrysoperla carnea (Stephens) (Neuroptera: Chrysopidae),” Journal of Insect Physiology 50, no. 2–3 (2004): 175–183.

[18] FAO-WHO, “Evaluation of Allergenicity of Genetically Modified Foods. Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology,” Jan. 22–25, 2001; http://www.fao.org/es/ESN/food/pdf/allergygm.pdf

[19] Gendel, “The use of amino acid sequence alignments to assess potential allergenicity of proteins used in genetically modified foods,” Advances in Food and Nutrition Research 42 (1998), 45–62.

[20] US EPA, “Biopesticides Registration Action Document (BRAD)—Bacillus thuringiensis Plant-Incorporated Protectants: Product Characterization & Human Health Assessment,” EPA BRAD (2001b) (October 15, 2001): IIB4, http://www.epa.gov/pesticides/biopesticides/pips/bt_brad2/2-id_health.pdf

[21] US EPA, “Biopesticides Registration Action Document (BRAD)—Bacillus thuringiensis Plant-Incorporated Protectants: Product Characterization & Human Health Assessment,” EPA BRAD (2001b) (October 15, 2001): IIB4, http://www.epa.gov/pesticides/biopesticides/pips/bt_brad2/2-id_health.pdf

[22] “Assessment of Additional Scientific Information Concerning StarLink Corn,” FIFRA Scientific Advisory Panel Report No. 2001-09, July 2001.

[23] EPA Scientific Advisory Panel, “Bt Plant-Pesticides Risk and Benefits Assessments,” March 12, 2001: 76. Available at: http://www.epa.gov/scipoly/sap/2000/october/octoberfinal.pdf

[24] Ashish Gupta et. al., “Impact of Bt Cotton on Farmers’ Health (in Barwani and Dhar District of Madhya Pradesh),” Investigation Report, Oct–Dec 2005.

[25] N. Tomlinson of UK MAFF’s Joint Food Safety and Standards Group 4, December 1998 letter to the U.S. FDA, commenting on its draft document, “Guidance for Industry: Use of Antibiotic Resistance Marker Genes in Transgenic Plants,” http://www.food.gov.uk/multimedia/pdfs/acnfp1998.pdf; (see pages 64–68).

[26] John M. Burns, “13-Week Dietary Subchronic Comparison Study with MON 863 Corn in Rats Preceded by a 1-Week Baseline Food Consumption Determination with PMI Certified Rodent Diet #5002,” December 17, 2002 http://www.monsanto.com/monsanto/content/sci_tech/prod_safety/fullratstudy.pdf, see also Stéphane Foucart, “Controversy Surrounds a GMO,” Le Monde, 14 December 2004; and Jeffrey M. Smith, “Genetically Modified Corn Study Reveals Health Damage and Cover-up,” Spilling the Beans, June 2005, http://www.seedsofdeception.com/Public/Newsletter/June05GMCornHealthDangerExposed/index.cfm

[27] A. Pusztai, et al, “Genetically Modified Foods: Potential Human Health Effects,” in: Food Safety: Contaminants and Toxins (ed. JPF D’Mello) (Wallingford Oxon, UK: CAB International), 347–372, also additional communication with Arpad Pusztai.

[28] October 24, 2005 correspondence between Arpad Pusztai and Brian John

GM Files: Rats Refuse GM Foods, FDA Says GMOs Dangerous, Approves Them

Friday, April 18th, 2008

The Natural Solutions Foundation, the leading Global Health Freedom organization, is proud to present this information to you. We protect your right to know about – and to use – natural ways to maintain and regain your health, no matter where in the world you live. Among your freedoms is the right to clean, unadulterated food free of genetic manipulation, pesticides, heavy metals or other contaminants and access to herbs, supplements, frequency devices and other means as therapies that may benefit or to protect your well-being without drugs and other dangerous interventions, if you choose.

For more information on our global programs, including the International Decade of Nutrition, and our US based ones, please visit us at www.HealthFreedomUSA.org and www.GlobalHealthFreedom.org and join the free email list for the Health Freedom eAlerts to keep you in the loop, informed and active defending your right to make your own decisions about your health and wellbeing!
Our activities are supported 100% by your tax deductible donations. Please give generously (http://www.healthfreedomusa.org/index.php?page_id=189) to the Natural Solutions Foundation. Thank you for your support.
Feel free to disseminate this information as widely as possible with full attribution.
Yours in health and freedom,
Dr. Rima

Rima E. Laibow, MD
Medical Director
Natural Solutions Foundation
www.HealthFreedomUSA.org
www.GlobalHealthFreedom.org
www.organics4U.orgProtect Yourself from Genetically Engineered Foods

By Jeffrey M. Smith, author of Seeds of Deception

In a study in the early 1990’s rats were fed genetically modified (GM) tomatoes. Well actually, the rats refused to eat them. They were force-fed. Several of the rats developed stomach lesions and seven out of forty died within two weeks.1 Scientists at the FDA who reviewed the study agreed that it did not provide a “demonstration of reasonable certainty of no harm.” In fact, agency scientists warned that GM foods in general might create unpredicted allergies, toxins, antibiotic resistant diseases, and nutritional problems. Internal FDA memos made public from a lawsuit reveal that the scientists urged their superiors to require long-term safety testing to catch these hard-to-detect side effects.2 But FDA political appointees, including a former attorney for Monsanto in charge of policy, ignored the scientists’ warnings. The FDA does not require safety studies. Instead, if the makers of the GM foods claim that they are safe, the agency has no further questions. The GM tomato was approved in 1994.
According to a July 27, 2004 report from the US National Academy of Sciences (NAS),3 the current system of blanket approval of GM foods by the FDA might not detect “unintended changes in the composition of the food.” The process of gene insertion, according to the NAS, could damage the host’s DNA with unpredicted consequences. The Indian Council of Medical Research (ICMR), which released its findings a few days earlier, identified a long list of potentially dangerous side effects from GM foods that are not being evaluated. The ICMR called for a complete overhaul of existing regulations.4
The safety studies conducted by the biotech industry are often dismissed by critics as superficial and designed to avoid finding problems. Tragically, scientists who voice their criticism, as well as those who have discovered incriminating evidence, have been threatened, stripped of responsibilities, denied funding or tenure, or fired.5 For example, a UK government-funded study demonstrated that rats fed a GM potato developed potentially pre-cancerous cell growth,6 damaged immune systems, partial atrophy of the liver, and inhibited development of their brains, livers and testicles.7 When the lead scientist went public with his concerns, he was promptly fired from his job after 35 years and silenced with threats of a lawsuit.
Americans eat genetically modified foods everyday. Although the GM tomato has been taken off the market, millions of acres of soy, corn, canola, and cotton have had foreign genes inserted into their DNA. The new genes allow the crops to survive applications of herbicide, create their own pesticide, or both. While there are only a handful of published animal safety studies, mounting evidence, which needs to be followed up, suggests that these foods are not safe.
Rats fed GM corn had problems with blood cell, kidney and liver formation.8 Mice fed GM soy had problems with liver cell formation9 and pancreatic function,10 and the livers of rats fed GM canola were heavier.11 Pigs fed GM corn on several Midwest farms developed false pregnancies or sterility.12 Cows fed GM corn in Germany died mysteriously. And twice the number of chickens died when fed GM corn compared to those fed natural corn.13
Soon after GM soy was introduced to the UK, soy allergies skyrocketed by 50 percent.14 Without follow-up tests, we can’t be sure if genetic engineering was the cause, but there are plenty of ways in which genetic manipulation can boost allergies.
A gene from a Brazil nut inserted into soybeans made the soy allergenic to those who normally react to Brazil nuts.15
GM soy currently consumed in the US contains a gene from bacteria. The inserted gene creates a protein that was never before part of the human food supply, and might be allergenic.
• Sections of that protein are identical to those found in shrimp and dust mite allergens.16 According to criteria recommended by the World Health Organization (WHO), this fact should have disqualified GM soy from approval.
• The sequence of the gene that was inserted into soy has inexplicably rearranged over time.17 The protein it creates is likely to be different than the one intended, and was never subject to any safety studies. It may be allergenic or toxic.
• The process of inserting the foreign gene damaged a section of the soy’s own DNA, scrambling its genetic code.18 This mutation might interfere with DNA expression or create a new, potentially dangerous protein.
• The most common allergen in soy is called trypsin inhibitor. GM soy contains significantly more of this compared with natural soy.19
The only human feeding study ever conducted showed that the gene inserted into soybeans spontaneously transferred out of food and into the DNA of gut bacteria.20 This has several serious implications. First, it means that the bacteria inside our intestines, newly equipped with this foreign gene, may create the novel protein inside of us. If it is allergenic or toxic, it may affect us for the long term, even if we give up eating GM soy.
The same study verified that the promoter, which scientists attach to the inserted gene to permanently switch it on, also transferred to gut bacteria. Research on this promoter suggests that it might unintentionally switch on other genes in the DNA—permanently.21 This could create an overproduction of allergens, toxins, carcinogens, or antinutrients. Scientists also theorize that the promoter might switch on dormant viruses embedded in the DNA or generate mutations.22
Unfortunately, gene transfer from GM food might not be limited to our gut bacteria. Preliminary results show that the promoter also transferred into rat organs, after they were fed only a single GM meal.23
This is only a partial list of what may go wrong with a single GM food crop. The list for others may be longer. Take for example, the corn inserted with a gene that creates its own pesticide. We eat that pesticide, and plenty of evidence suggests that it is not as benign as the biotech proponents would have us believe. Preliminary evidence, for example, shows that thirty-nine Philippinos living next to a pesticide-producing cornfield developed skin, intestinal, and respiratory reactions while the corn was pollinating. Tests of their blood also showed an immune response to the pesticide.24 Consider what might happen if the gene that produces the pesticide were to transfer from the corn we eat into our gut bacteria. It could theoretically transform our intestinal flora into living pesticide factories.
GM corn and most GM crops are also inserted with antibiotic resistant genes. The ICMR, along with the American Medical Association, the WHO, and organizations worldwide, have expressed concern about the possibility that these might transfer to pathogenic bacteria inside our gut. They are afraid that it might create new, antibiotic resistant super-diseases. The defense that the biotech industry used to counter these fears was that the DNA was fully destroyed during digestion and therefore no such transfer of genes was possible. The human feeding study described above, published in February 2004, overturned this baseless assumption.
No one monitors human health impacts of GM foods. If the foods were creating health problems in the US population, it might take years or decades before we identified the cause. One epidemic in the 1980’s provides a chilling example. A new disease was caused by a brand of the food supplement L-tryptophan, which had been created through genetic modification and contained tiny traces of contaminants. The disease killed about 100 Americans and caused sickness or disability in about 5-10,000 others.25 The only reason that doctors were able to identify that an epidemic was occurring, was because the disease had three simultaneous characteristics: it was rare, acute, and fast acting. Even then it was nearly missed entirely.
Studies show that the more people learn about GM foods, the less they trust them.26 In Europe, Japan, and other regions, the press has been far more open about the potential dangers of genetic manipulation. Consequently, consumers there demand that their food supply be GM-free and manufacturers comply. But in the US, most people believe they have never eaten a GM food in their lives27 (even though they consume them daily). Lacking awareness, complacent consumers have been the key asset for the biotech industry in the US. As a result, millions of Americans are exposed to the potential dangers, and children are most at risk. Perhaps the revelations in the reports released on opposite sides of the planet will awaken consumers as well as regulators, and GM foods on the market will be withdrawn.

This is the first in a series of articles by Jeffrey Smith. To learn more about GM foods and how to avoid them, to download a letter to food manufacturers, and to receive a free monthly electronic newsletter with the rest of the series, go to www.seedsofdeception.com.
Jeffrey M. Smith is the author of Seeds of Deception: Exposing Industry and Government Lies about the Safety of the Genetically Engineered Foods You’re Eating, and the Director of the Institute for Responsible Technology. He has traveled to five continents to inform world leaders and the public on the documented risks of genetically modified foods and crops and the controversies surrounding their approval. See www.seedsofdeception.com for the current tour schedule.
(References available at www.seedsofdeception.com)
© Copyright 2004 by Jeffrey M. Smith. Permission is granted to reproduce this in whole or in part.
References
1. Pusztai, A. et al. (2003) Genetically Modified Foods: Potential Human Health Effects. In: Food Safety: Contaminants and Toxins (ed. JPF D’Mello) pp. 347-372. CAB International, Wallingford Oxon, UK
2. www.biointegrity.org
3. SAFETY OF GENETICALLY ENGINEERED FOODS: APPROACHES TO ASSESSING UNINTENDED HEALTH EFFECTS, Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health, Institute of Medicine and National Research Council of the National Academies, THE NATIONAL ACADEMIES PRESS, Washington, D.C., 2004
4. Ashok B. Sharma, “ICMR Wants Overhaul Of GM Foods Regulation,” Financial Express, New Delhi, India July 25, 2004
5. Jeffrey M. Smith, Seeds of Deception, Yes! Books, Iowa, US, 2003
6. Ewen, SWB & Pusztai, A. (1999) Effects of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet 354, 1727-1728.
7. Personal communication with Arpad Pusztai.
8. French experts very disturbed by health effects of Monsanto GM corn (24/4/2004), www.gmwatch.org/archive2.asp?arcid=3308, Translation of Le Monde article “L’expertise confidentielle sur un inquiétant maïs transgénique,” Confidential report on a worrying GM corn by Herve Kempf, 22.04.04, www.lemonde.fr/web/article/0,1-0@2-3226,36-362061,0.html. Also see Spilling the Beans, June 2005, www.seedsofdeception.com/Public/Newsletter/June05GMCornHealthDangerExposed/index.cfm
9. Malatesta M, Caporaloni C, Gavaudan S, et al “Ultrastructural Morphometrical and Immunocytochemical Analyses of Hepatocyte Nuclei from Mice Fed on Genetically Modified Soybean”. Cell Structure and Function Vol. 27 (2002), No. 4, pp. 173-18. www.gmwatch.org/archive2.asp?arcid=3622
10. Manuela Malatesta, et al, Ultrastructural analysis of pancreatic acinar cells from mice fed on genetically modified soybean, Journal of Anatomy, Volume 201 Issue 5 p. 409, November 2002
11. Advisory Committee on Releases to the Environment, Advice on a notification for marketing of herbicide tolerant GM oilseed rape, www.defra.gov.uk/environment/acre/advice/pdf/acre_advice36.pdf
12. www.savejerryscorn.org/
13. Report for the Chardon LL Hearing, Non-Suitability of Genetically Engineered Feed for Animals, Dr. Eva Novotny, Scientists for Global Responsibility, May 2002, www.sgr.org.uk/GenEng/animalfeel_all.pdf
14. Mark Townsend, “Why soya is a hidden destroyer,” Daily Express, March 12, 1999
15. J Ordlee, et al, “Identification of a Brazil-Nut Allergen in Transgenic Soybeans,” The New Englandd Journal of Medicine, March 14, 1996
16. G. A. Kleter and A. A. C. M. Peijnenburg, “Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences indentical to potential, IgE-binding linear epitopes of allergens,” BMC Structural Biology, vol. 2, 2002, p. 8-19
17. Mae-Wan Ho, Transgenic Lines Proven Unstable, www.i-sis.org.uk/TLPU.php about Collonier C, et al, Characterization of commercial GMO inserts: a source of useful material to study genome fluidity. Poster courtesy of Pr. Gilles-Eric Seralini, Président du Conseil Scientifique du CRII-GEN, www.crii-gen.org
18. P. Windels, I. Taverniers, A. Depicker, E. Van Bockstaele, and M. DeLoose, “Characterisation of the Roundup Ready soybean insert,” European Food Research and Technology, vol. 213, 2001, pp. 107-112
19. Stephen R. Padgette and others, “The Composition of Glyphosate-Tolerant Soybean Seeds Is Equivalent to That of Conventional Soybeans,” The Journal of Nutrition, vol. 126, no. 4, April 1996 (Data was taken from the journal archives, as they had been omitted from the published study. It was reported by Barbara Keeler and Marc Lappé, “Some Food for FDA Regulation,” Los Angeles Times, January 7, 2001)
20. Netherwood, et al, Assessing the survival of transgenic plant DNA in the human gastrointestinal tract, Nature Biotechnology, Vol 22 Number 2 February 2004.
21. Michael Hansen, “Possible Human Health Hazards of Genetically Engineered Bt Crops: Comments on the human health and product characterization sections of EPA’s Bt Plant-Pesticides Biopesticides Registration Action Document,” Presented to the EPA Science Advisory Panel Arlington, VA, October 20, 2000
22. Mae-Wan Ho, Angela Ryan and Joe Cummins, “Cauliflower Mosaic Viral Promoter—A Recipe for Disaster?” Institute of Science in Society, www.i-sis.org.uk/camvrecdis.php
23. Jeffrey M. Smith, The cauliflower mosaic virus (CaMV) promoter was found intact in rat tissues after a single meal, and was also confirmed to be active in human cells, Press Release, February 2004, www.seedsofdeception.com/Media-rattissue.php
24. Jeffrey M. Smith, Bt-maize (corn) during pollination, may trigger disease in people living near the cornfield, Press Release February 2004, www.seedsofdeception.com/Media-maizepollen.php and Allen V. Estabillo, Farmer’s group urges ban on planting Bt corn; says it could be cause of illnesses, Mindanews / 19 October 2004, www.seedsofdeception.com/Media-update-Philippines-BT-corn.php
25. Jeffrey M. Smith, “Deadly Epidemic,” Chapter 4 in Seeds of Deception, Yes! Books, Iowa, US, 2003
26. GM Nation? The findings of the public debate, www.gmnation.org.uk/ut_09/ut_9_6.htm#summary
27. Public Sentiment About Genetically Modified Food, September 2003 Update, Pew Initiative on Food and Biotechnology, http://pewagbiotech.org/research/2003update

GM Files: Unintended Health Risks of GMOs

Friday, April 18th, 2008

The Natural Solutions Foundation, the leading Global Health Freedom organization, is proud to present this information to you. We protect your right to know about – and to use – natural ways to maintain and regain your health, no matter where in the world you live. Among your freedoms is the right to clean, unadulterated food free of genetic manipulation, pesticides, heavy metals or other contaminants and access to herbs, supplements, frequency devices and other means as therapies that may benefit or to protect your well-being without drugs and other dangerous interventions, if you choose.

For more information on our global programs, including the International Decade of Nutrition, and our US based ones, please visit us at www.HealthFreedomUSA.org and www.GlobalHealthFreedom.org and join the free email list for the Health Freedom eAlerts to keep you in the loop, informed and active defending your right to make your own decisions about your health and wellbeing!
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Feel free to disseminate this information as widely as possible with full attribution.
Yours in health and freedom,
Dr. Rima

Rima E. Laibow, MD
Medical Director
Natural Solutions Foundation
www.HealthFreedomUSA.org
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www.organics4U.org

Unintended GMO Health Risks

Genetically modified foods:

YES, you are already eating them.
NO, they are not safe to eat.

Did you know… since 1996 Americans have been eating genetically modified (GM) ingredients in most processed foods.

Did you know… GM plants, such as soybean, corn, cottonseed, and canola have had foreign genes forced into their DNA. And the inserted genes come from species, such as bacteria and viruses, that have never been in the human food supply.

Did you know… genetically modified organisms (GMOs) are not safe. They have been linked to thousands of toxic and allergenic reactions, thousands of sick, sterile, and dead livestock, and damage to virtually every organ and system studied in lab animals.

Find out what the risks are and start protecting yourself and your family today!

Why isn’t the FDA protecting us?

In 1992, the Food and Drug Administration claimed that they had no information showing that GM foods were substantially different from conventionally grown foods and therefore were safe to eat. But internal memos made public by a lawsuit reveal that their position was staged by political appointees under orders from the White House to promote GMOs. FDA scientists, on the other hand, warned that GMOs can create unpredictable, hard-to-detect side effects, including allergies, toxins, new diseases, and nutritional problems. They urged long term safety studies, but were ignored.[1] The FDA does not require any safety evaluations for GMOs. Instead, biotech companies, who have been found guilty of hiding toxic effects of their chemical products, are now in charge of determining whether their GM foods are safe. (The FDA official in charge of creating this policy was Michael Taylor, Monsanto’s former attorney and later their vice president.)

Although these biotech companies participate in a voluntary consultation process with the FDA, it is a meaningless exercise. The summaries of the superficial research they submit cannot identify most of the health risks of GMOs.[2]

Genetic modification is radically different from natural breeding

In contrast to the statements of biotech advocates, FDA scientists and others affirm that genetic modification is not just an extension of the conventional breeding techniques that have been used by farmers for millennia. Genetic engineering transfers genes across natural species barriers, using imprecise laboratory techniques that bear no resemblance to natural breeding. Furthermore, the technology is based on outdated concepts of how genes and cells work.[3]

Widespread, unpredictable changes

Gene insertion is done either by shooting genes from a “gene gun” into a plate of cells or by using bacteria to invade the cell with foreign DNA. The altered cell is then cloned into a plant. These processes create massive collateral damage, causing mutations in hundreds or thousands of locations throughout the plant’s DNA.[4] Natural genes can be deleted or permanently turned on or off, and hundreds may change their levels of expression.[5]

In addition:

*
The inserted gene is often rearranged;[6]
* It may transfer from the food into our body’s cells or into the DNA of bacteria inside us;[7] and
* The GM protein produced by the gene may have unintended properties or effects.

GM foods on the market

The primary reason companies genetically engineer plants is to make them tolerant to their brand of herbicide. The four major GM plants, soy, corn, canola, and cotton, are designed to survive an otherwise deadly dose of weed killer. These crops have much higher residues of toxic herbicides. About 68% of GM crops are herbicide tolerant.

The second GM trait is a built-in pesticide. A gene from the soil bacterium called Bt (for Bacillus thuringiensis) is inserted into corn and cotton DNA, where it secretes the insect-killing Bt-toxin in every cell. About 19% of GM crops produce their own pesticide. Another 13% produce a pesticide and are herbicide tolerant.

There is also Hawaiian papaya and a small amount of zucchini and yellow crookneck squash, which are engineered to resist a plant virus. Help stop the introduction of GM sugar in late 2008. Send a letter to top companies on our website.

Growing evidence of harm from GMOs
GM soy and allergic reactions

* Soy allergies skyrocketed by 50% in the UK, soon after GM soy was introduced.[8]
* A human subject showed a skin prick allergic-type reaction to GM soy, but not to natural soy.[9]
* The level of one known soy allergen is as much as 7-times higher in cooked GM soy compared to non-GM soy.[10]
* GM soy also contains an unexpected allergen-type protein not found in natural soy.[11]

Bt corn and cotton linked to allergies

The biotech industry claims that Bt-toxin is harmless to humans and mammals because the natural bacteria version has been used as a spray by farmers for years. In reality, hundreds of people exposed to Bt spray had allergic-type symptoms,[12] and mice fed Bt had powerful immune responses[13] and damaged intestines.[14] Moreover, Bt in GM crops is designed to be more toxic than the natural spray and is thousands of times more concentrated.

Hundreds of laborers in India report allergic reactions from handling Bt cotton.[15] Their symptoms are identical to those exposed to Bt spray.[16]

GMOs fail allergy tests

No tests can guarantee that a GMO will not cause allergies. Although the World Health Organization recommends a protein screening protocol,[17] the GM soy, corn, and papaya in our food supply fail those tests— because they have properties of known allergens.[18]

GMOs cause immune reactions to non-GM foods

* If proteins “digest” slowly, there is more time for allergic reactions. Because GM soy reduces digestive enzymes in mice,[19] it may slow protein digestion and promote allergies to many foods.
* Mice not only reacted to Bt -toxin, they had immune responses to formerly harmless compounds.[20]
* Similarly, a mouse test indicated that people eating GM peas could develop allergies both to the peas and to a range of other foods. The peas had already passed all the allergy tests normally used to get GMOs on the market. It took this advanced mouse test, which was never used on the GMOs we eat, to discover that the peas could be deadly.[21]

GMOs and liver problems

* Rats fed GM potatoes had smaller, partially atrophied livers.[22]
* The livers of rats fed GM canola were 12-16% heavier.[23]
* GM soy altered mouse liver cells in ways that suggest a toxic insult.[24] The changes reversed after their diet switched to non-GM soy.[25]

GM soy, reproductive problems, and infant mortality

* More than half the offspring of mother rats fed GM soy died within three weeks.[26]
* Male rats[27] and mice[28] fed GM soy showed changes in their testicles; the mice had altered young sperm cells.
* The DNA of mouse embryos whose parents ate GM soy functioned differently than those whose parents ate non-GM soy.[29]

Many offspring of female rats fed GM soy were considerably
smaller,and more than half died within three weeks (compared
to 10% of the non-GM soy controls). [30]

Bt crops linked to sterility, disease, and death

* When sheep grazed on Bt cotton plants after harvest, within a week 1 in 4 died. Shepherds estimate 10,000 sheep deaths in one region of India.[31]
* Farmers in Europe and Asia say that cows, water buffaloes, chickens, and horses died from eating Bt corn varieties.[32]
* About two dozen US farmers report that Bt corn varieties caused widespread sterility in pigs or cows.[33]
* Filipinos in at least five villages fell sick when a nearby Bt corn variety was pollinating.[34]

The stomach lining of rats fed GM potatoes showed excessive cell growth, a condition that may be a precursor to cancer. Rats also had damaged organs and immune systems.[35]

Functioning GM genes remain inside you

Unlike safety evaluations for drugs, there are no human clinical trials of GM foods. The only published human feeding experiment verified that genetic material inserted into GM soy transfers into the DNA of intestinal bacteria and continues to function.[36] This means that long after we stop eating GM foods, we may still have their GM proteins produced continuously inside us.

* If the antibiotic gene inserted into most GM crops were to transfer, it could create super diseases, resistant to antibiotics.
* If the gene that creates Bt -toxin in GM corn were to transfer, it might turn our intestinal flora into living pesticide factories.
* Animal studies show that DNA in food can travel into organs throughout the body, even into the fetus.[37]

GM food supplement caused deadly epidemic

In the 1980s, a contaminated brand of a food supplement called L-tryptophan killed about 100 Americans and caused sickness and disability in another 5,000-10,000 people. The source of contaminants was almost certainly the genetic engineering process used in its production.[38] The disease took years to find and was almost overlooked. It was only identified because the symptoms were unique, acute, and fast-acting. If all three characteristics were not in place, the deadly GM supplement might never have been identified or removed.

If GM foods on the market are causing common diseases or if their effects appear only after long-term exposure, we may not be able to identify the source of the problem for decades, if at all. There is no monitoring of GMO-related problems and no long-term animal studies. Heavily invested biotech corporations are gambling away the health of our nation for profit.

Help end the genetic engineering of our food supply

When the tipping point of consumer concern about GMOs was achieved in Europe in 1999, within a single week virtually all major food manufacturers committed to remove GM ingredients. The Campaign for Healthier Eating in America is designed to reach a similar tipping point in the US before the end of 2009.

Our growing network of manufacturers, retailers, healthcare practitioners, organizations, and the media, is informing consumers of the health risks of GMOs and helping them select healthier non-GMO alternatives.

Go to www.responsibletechnology.org to get involved and learn how to avoid GMOs. Look for our Non-GMO Shopping Guide in summer 2008.

Start buying non-GMO today.

Help us stop the genetic engineering of our food supply.

Donations to the Institute For Responsible Technology are tax-deductible. Your $25 membership includes a free educational gift.
There are three ways to become a member or make a donation:

1.
By mail: Institute For Responsible Technology, P.O. Box 469, Fairfield, IA 52556
2.
Online: www.responsibletechnology.org
3.
By phone: (641) 209-1765

The health information is from the book Genetic Roulette: The Documented Health Risk of Genetically Engineered Foods, by Jeffrey M. Smith.

© copyright Institute For Responsible Technology 2008. The Institute is a fully tax deductible project of The Coordinating Council, a 501c(3).
[1] See www.biointegrity.org
[2] See Part 2, Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods, Yes! Books, Fairfield, IA 2007
[3] See for example 233-236, chart of disproved assumptions, in Jeffrey M. Smith, Genetic Roulette: The Documented Health Risks of Genetically Engineered Foods, Yes! Books, Fairfield, IA 2007
[4] J. R. Latham, et al., “The Mutational Consequences of Plant Transformation,” The Journal of Biomedicine and Biotechnology 2006, Article ID 25376: 1-7; see also Allison Wilson, et. al., “Transformation-induced mutations in transgenic plants: Analysis and biosafety implications,” Biotechnology and Genetic Engineering Reviews – Vol. 23, December 2006.
[5] Srivastava, et al, “Pharmacogenomics of the cystic fibrosis transmembrane conductance regulator (CFTR) and the cystic fibrosis drug CPX using genome microarray analysis,” Mol Med. 5, no. 11(Nov 1999):753–67.
[6] Latham et al, “The Mutational Consequences of Plant Transformation, Journal of Biomedicine and Biotechnology 2006:1-7, article ID 25376, http://www.hindawi.com/journals/JBB/index.html; Draft risk analysis report application A378, Food derived from glyphosate-tolerant sugarbeet line 77 (GTSB77),” ANZFA, March 7, 2001, www.agbios.com/docroot/decdocs/anzfa_gtsb77.pdf; E. Levine et al., “Molecular Characterization of Insect Protected Corn Line MON 810.” Unpublished study submitted to the EPA by Monsanto, EPA MRID No. 436655-01C (1995); Allison Wilson, PhD, Jonathan Latham, PhD, and Ricarda Steinbrecher, PhD, “Genome Scrambling—Myth or Reality? Transformation-Induced Mutations in Transgenic Crop Plants Technical Report—October 2004,” www.econexus.info; C. Collonier, G. Berthier, F. Boyer, M. N. Duplan, S. Fernandez, N. Kebdani, A. Kobilinsky, M. Romanuk, Y. Bertheau, “Characterization of commercial GMO inserts: a source of useful material to study genome fluidity,” Poster presented at ICPMB: International Congress for Plant Molecular Biology (n°VII), Barcelona, 23-28th June 2003. Poster courtesy of Dr. Gilles-Eric Seralini, Président du Conseil Scientifique du CRII-GEN, www.crii-gen.org; also “Transgenic lines proven unstable” by Mae-Wan Ho, ISIS Report, 23 October 2003, www.i-sis.org.uk
[7] Netherwood et al, “Assessing the survival of transgenic plant DNA in the human gastrointestinal tract,” Nature Biotechnology 22 (2004): 2; Chowdhury, et al, “Detection of genetically modified maize DNA fragments in the intestinal contents of pigs fed StarLink CBH351,” Vet Hum Toxicol. 45 , no. 2 (March 2003): 95–6; P. A. Chambers, et al, “The fate of antibiotic resistance marker genes in transgenic plant feed material fed to chickens,” J. Antimic. Chemother. 49 (2000): 161–164; and Paula S. Duggan, et al, “Fate of genetically modified maize DNA in the oral cavity and rumen of sheep,” Br J Nutr. 89, no 2 (Feb.2003): 159–66.
[8] Mark Townsend, “Why soya is a hidden destroyer,” Daily Express, March 12, 1999.
[9] Hye-Yung Yum, Soo-Young Lee, Kyung-Eun Lee, Myung-Hyun Sohn, Kyu-Earn Kim, “Genetically Modified and Wild Soybeans: An immunologic comparison,” Allergy and Asthma Proceedings 26, no. 3 (May–June 2005): 210-216(7).
[10] A. Pusztai and S. Bardocz, “GMO in animal nutrition: potential benefits and risks,” Chapter 17, Biology of Nutrition in Growing Animals, R. Mosenthin, J. Zentek and T. Zebrowska (Eds.) Elsevier, October 2005.
[11] Hye-Yung Yum, Soo-Young Lee, Kyung-Eun Lee, Myung-Hyun Sohn, Kyu-Earn Kim, “Genetically Modified and Wild Soybeans: An immunologic comparison,” Allergy and Asthma Proceedings 26, no. 3 (May–June 2005): 210-216(7).
[12] M. Green, et al., “Public health implications of the microbial pesticide Bacillus thuringiensis: An epidemiological study, Oregon, 1985-86,” Amer. J. Public Health 80, no. 7(1990): 848–852; and M.A. Noble, P.D. Riben, and G. J. Cook, Microbiological and epidemiological surveillance program to monitor the health effects of Foray 48B BTK spray (Vancouver, B.C.: Ministry of Forests, Province of British Columbi, Sep. 30, 1992)
[13] Vazquez et al, “Intragastric and intraperitoneal administration of Cry1Ac protoxin from Bacillus thuringiensis induces systemic and mucosal antibody responses in mice,” 1897–1912; Vazquez et al, “Characterization of the mucosal and systemic immune response induced by Cry1Ac protein from Bacillus thuringiensis HD 73 in mice,” Brazilian Journal of Medical and Biological Research 33 (2000): 147–155; and Vazquez et al, “Bacillus thuringiensis Cry1Ac protoxin is a potent systemic and mucosal adjuvant,” Scandanavian Journal of Immunology 49 (1999): 578–584. See also Vazquez-Padron et al., 147 (2000b).
[14] Nagui H. Fares, Adel K. El-Sayed, “Fine Structural Changes in the Ileum of Mice Fed on Endotoxin Treated Potatoes and Transgenic Potatoes,” Natural Toxins 6, no. 6 (1998): 219–233.
[15] See for example “Bt cotton causing allergic reaction in MP; cattle dead,” Bhopal, Nov. 23, 2005, http://news.webindia123.com/news/showdetails.asp?id=170692&cat=Health;
[16] Ashish Gupta et. al., “Impact of Bt Cotton on Farmers’ Health (in Barwani and Dhar District of Madhya Pradesh),” Investigation Report, Oct–Dec 2005; and M. Green, et al., “Public health implications of the microbial pesticide Bacillus thuringiensis: An epidemiological study, Oregon, 1985-86,” Amer. J. Public Health 80, no. 7(1990): 848–852; and M.A. Noble, P.D. Riben, and G. J. Cook, Microbiological and epidemiological surveillance program to monitor the health effects of Foray 48B BTK spray (Vancouver, B.C.: Ministry of Forests, Province of British Columbi, Sep. 30, 1992)
[17] FAO-WHO, “Evaluation of Allergenicity of Genetically Modified Foods. Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology,” Jan. 22–25, 2001; http://www.fao.org/es/ESN/food/pdf/allergygm.pdf
[18] Gendel, “The use of amino acid sequence alignments to assess potential allergenicity of proteins used in genetically modified foods,” Advances in Food and Nutrition Research 42 (1998), 45–62; G. A. Kleter and A. A. C. M. Peijnenburg, “Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences indentical to potential, IgE-binding linear epitopes of allergens,” BMC Structural Biology 2 (2002): 8–19; H. P. J. M. Noteborn, “Assessment of the Stability to Digestion and Bioavailability of the LYS Mutant Cry9C Protein from Bacillus thuringiensis serovar tolworthi,” Unpublished study submitted to the EPA by AgrEvo, EPA MRID No. 447343-05 (1998); and H. P. J. M. Noteborn et al, “Safety Assessment of the Bacillus thuringiensis Insecticidal Crystal Protein CRYIA(b) Expressed in Transgenic Tomatoes,” in Genetically modified foods: safety issues, American Chemical Society Symposium Series 605, eds. K.H. Engel et al., (Washington, DC, 1995): 134–47.
[19] M. Malatesta, M. Biggiogera, E. Manuali, M. B. L. Rocchi, B. Baldelli, G. Gazzanelli, “Fine Structural Analyses of Pancreatic Acinar Cell Nuclei from Mice Fed on GM Soybean,” Eur J Histochem 47 (2003): 385–388.
[20] Vazquez et al, “Bacillus thuringiensis Cry1Ac protoxin is a potent systemic and mucosal adjuvant,” Scandanavian Journal of Immunology 49 (1999): 578–584. See also Vazquez-Padron et al., 147 (2000b).
[21] V. E. Prescott, et al, “Transgenic Expression of Bean r-Amylase Inhibitor in Peas Results in Altered Structure and Immunogenicity,” Journal of Agricultural Food Chemistry (2005): 53.
[22] Arpad Pusztai, “Can science give us the tools for recognizing possible health risks of GM food,” Nutrition and Health, 2002, Vol 16 Pp 73-84
[23] Comments to ANZFA about Applications A346, A362 and A363 from the Food Legislation and Regulation Advisory Group (FLRAG) of the Public Health Association of Australia (PHAA) on behalf of the PHAA, “Food produced from glyphosate-tolerant canola line GT73,” http://www.iher.org.au/
[24] M. Malatesta, C. Caporaloni, S. Gavaudan, M. B. Rocchi, S. Serafini, C. Tiberi, G. Gazzanelli, “Ultrastructural Morphometrical and Immunocytochemical Analyses of Hepatocyte Nuclei from Mice Fed on Genetically Modified Soybean,” Cell Struct Funct. 27 (2002): 173–180.
[25] M. Malatesta, C. Tiberi, B. Baldelli, S. Battistelli, E. Manuali, M. Biggiogera, “Reversibility of Hepatocyte Nuclear Modifications in Mice Fed on Genetically Modified Soybean,” Eur J Histochem, 49 (2005): 237-242.
[26] I.V. Ermakova, “Diet with the Soya Modified by Gene EPSPS CP4 Leads to Anxiety and Aggression in Rats,” 14th European Congress of Psychiatry. Nice, France, March 4-8, 2006; “Genetically modified soy affects posterity: Results of Russian scientists’ studies,” REGNUM, October 12, 2005; http://www.regnum.ru/english/526651.html; Irina Ermakova, “Genetically modified soy leads to the decrease of weight and high mortality of rat pups of the first generation. Preliminary studies,” Ecosinform 1 (2006): 4–9.
[27] Irina Ermakova, “Experimental Evidence of GMO Hazards,” Presentation at Scientists for a GM Free Europe, EU Parliament, Brussels, June 12, 2007
[28] L. Vecchio et al, “Ultrastructural Analysis of Testes from Mice Fed on Genetically Modified Soybean,” European Journal of Histochemistry 48, no. 4 (Oct–Dec 2004):449–454.
[29] Oliveri et al., “Temporary Depression of Transcription in Mouse Pre-implantion Embryos from Mice Fed on Genetically Modified Soybean,” 48th Symposium of the Society for Histochemistry, Lake Maggiore (Italy), September 7–10, 2006.
[30] I.V. Ermakova, “Diet with the Soya Modified by Gene EPSPS CP4 Leads to Anxiety and Aggression in Rats,” 14th European Congress of Psychiatry. Nice, France, March 4-8, 2006; “Genetically modified soy affects posterity: Results of Russian scientists’ studies,” REGNUM, October 12, 2005; http://www.regnum.ru/english/526651.html; Irina Ermakova, “Genetically modified soy leads to the decrease of weight and high mortality of rat pups of the first generation. Preliminary studies,” Ecosinform 1 (2006): 4–9.
[31] “Mortality in Sheep Flocks after Grazing on Bt Cotton Fields—Warangal District, Andhra Pradesh” Report of the Preliminary Assessment, April 2006, http://www.gmwatch.org/archive2.asp?arcid=6494
[32] Mae-Wan Ho, “GM Ban Long Overdue, Dozens Ill & Five Deaths in the Philippines,” ISIS Press Release, June 2, 2006; and Mae-Wan Ho and Sam Burcher, “Cows Ate GM Maize & Died,” ISIS Press Release, January 13, 2004, http://www.isis.org.uk/CAGMMAD.php
[33] Personal communication with Jerry Rosman and other farmers, 2006; also reported widely in the farm press.
[34] See for example Mae-Wan Ho, “GM Ban Long Overdue, Dozens Ill & Five Deaths in the Philippines,” ISIS Press Release, June 2, 2006; “Study Result Not Final, Proof Bt Corn Harmful to Farmers,” BusinessWorld, 02 Mar 2004; and “Genetically Modified Crops and Illness Linked,” Manila Bulletin, 04 Mar 2004.
[35] Arpad Pusztai, “Can science give us the tools for recognizing possible health risks of GM food,” Nutrition and Health, 2002, Vol 16 Pp 73-84; Stanley W. B. Ewen and Arpad Pusztai, “Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine,” Lancet, 1999 Oct 16; 354 (9187): 1353-4; and Arpad Pusztai, “Facts Behind the GM Pea Controversy: Epigenetics, Transgenic Plants & Risk Assessment,” Proceedings of the Conference, December 1st 2005 (Frankfurtam Main, Germany: Literaturhaus, 2005)
[36] Netherwood et al, “Assessing the survival of transgenic plant DNA in the human gastrointestinal tract,” Nature Biotechnology 22 (2004): 2.
[37] Ricarda A. Steinbrecher and Jonathan R. Latham, “Horizontal gene transfer from GM crops to unrelated organisms,” GM Science Review Meeting of the Royal Society of Edinburgh on “GM Gene Flow: Scale and Consequences for Agriculture and the Environment,” January 27, 2003; Traavik and Heinemann, Genetic Engineering and Omitted Health Research; citing Schubbert, et al, “Ingested foreign (phage M13) DNA survives transiently in the gastrointestinal tract and enters the bloodstream of mice,” Mol Gen Genet. 242, no. 5 (1994): 495–504; Schubbert et al, “Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA,” Proc Natl Acad Sci USA 94, no. 3 (1997): 961–6; Schubbert et al, “On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus,” Mol Gen Genet. 259, no. 6 (1998): 569–76; Hohlweg and Doerfler, “On the fate of plants or other foreign genes upon the uptake in food or after intramuscular injection in mice,” Mol Genet Genomics 265 (2001): 225–233; Palka-Santani, et al., “The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DNA and proteins,” Mol Gen Genomics 270 (2003): 201–215; Einspanier, et al, “The fate of forage plant DNA in farm animals; a collaborative case-study investigating cattle and chicken fed recombinant plant material,” Eur Food Res Technol 212 (2001): 129–134; Klotz, et al, “Degradation and possible carry over of feed DNA monitored in pigs and poultry,” Eur Food Res Technol 214 (2002): 271–275; Forsman, et al, “Uptake of amplifiable fragments of retrotransposon DNA from the human alimentary tract,” Mol Gen Genomics 270 (2003): 362–368; Chen, et al, “Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles,” World Journal of Gastroenterology 10, no 1(2004): 112–116; Phipps, et al, “Detection of transgenic and endogenous plant DNA in rumen fluid, duodenal digesta, milk, blood, and feces of lactating dairy cows,” J Dairy Sci. 86, no. 12(2003): 4070–8.
[38] William E. Crist, Toxic L-tryptophan: Shedding Light on a Mysterious Epidemic, http://www.seedsofdeception.com/Public/L-tryptophan/index.cfm; and Jeffrey M. Smith, Seeds of Deception, Yes! Books, Fairfield, IA 2003, chapter 4, Deadly Epidemic.